Xenbase Image ID: 133742

Fig. 2. SSCs express tph1. (A) Expression pattern of tph1 mRNA at stage 31. Signals were detected in the brain and in a punctate pattern in the epidermis. A sagittal histological section (A′) demonstrated tph1expression in the epiphysis (A′) in SSCs and in a subset of neuronal cells (n) in the floor plate of the neural tube (A′′). (B) SSCs express tph1 (blue arrowhead), as demonstrated by whole-mount in situ hybridization followed by IF for serotonin (green, green arrowhead) and cilia (acetylated-α-tubulin, red, red arrowhead). (C) Punctate expression pattern of aromatic-L-amino-acid decarboxylase (DOPA-decarboxylase; ddc) in the embryonic skin. Inset shows close-up. Embryos are shown in lateral views. a, anterior; d, dorsal; epi, epiphysis; l, left; r, right. Image published in: Walentek P et al. (2014) Copyright © 2014. Image reproduced with permission of the Publisher. Gene Synonyms Species Stage(s) Tissue tph1.L X. laevis Throughout NF stage 31 epidermis epithelium pineal gland secretory epithelial cell neuron floor plate ciliated cell ddc.L LOC121395060 X. laevis Throughout NF stage 33 and 34 epidermis skin head Image source: Published Larger Image Printer Friendly View

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