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Fig. 4. Developmental expression pattern of selected Pax3-Zic1 targets. The spatiotemporal expression pattern of 10 Pax3-Zic1 targets was analyzed by qPCR and whole-mount ISH. Expression levels of the target genes were analyzed by qPCR at the indicated stage (right panels). The values were normalized to odc and presented as mean±s.d. The data are an average of at least three sets of embryos. For ISH embryos were analyzed at the neurula (left panels; dorsal view, anterior to top) and tailbud (middle panels; lateral and dorsal views, anterior to the left) stages. Image published in: Bae CJ et al. (2014) Copyright © 2014. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue pdgfra.L pdgfr2, pdgfr-alpha, pdgfralpha X. laevis Sometime during NF stage 14 to NF stage 24 cranial neural crest mandibular crest hyoid crest branchial crest posterior premigratory neural crest cell ak3.L ak6 X. laevis Sometime during NF stage 14 to NF stage 25 neural crest cranial neural crest premigratory neural crest cell branchial crest trunk neural tube spinal cord pmp22.L cmt1a, cmt1e, dss, gas-3, hmsnia, hnpp, sp110 X. laevis Sometime during NF stage 14 to NF stage 25 somite mandibular arch trigeminal placode paraxial mesoderm p2ry4.L XlP2Y X. laevis Sometime during NF stage 14 to NF stage 25 neural crest neural plate border cranial neural crest mandibular arch tspan18.S X. laevis Sometime during NF stage 14 to NF stage 25 somite lmx1b.S lmx1.2, lmx1b.1, nps1, Xlmx1b X. laevis Sometime during NF stage 14 to NF stage 25 neural plate border pre-chordal neural plate border rassf10.L LOC100141316 X. laevis Sometime during NF stage 14 to NF stage 25 neural plate border neural tube optic vesicle brain midbrain hindbrain cement gland primordium pnhd.L pinhead X. laevis Sometime during NF stage 14 to NF stage 25 neural plate border brain neural plate npr3.L npr-c, nprc X. laevis Sometime during NF stage 14 to NF stage 26 optic vesicle trigeminal placode trunk neural crest mfap2.L magp, magp-1, magp1, mfap2-a, mfap2-b X. laevis Throughout NF stage 15 neural plate mfap2.L magp, magp-1, magp1, mfap2-a, mfap2-b X. laevis Throughout NF stage 24 pharyngeal arch mandibular arch hyoid arch branchial arch cranial neural crest spinal cord trunk neural crest Image source: Published Larger Image Printer Friendly View

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