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Fig. S3. Expression analysis of mechanistic target of rapamycin complex 1 (mTORC1) signaling components. Whole-mount in situ hybridizations and paraplast sections thereof comparing mtor (A–B′′), tuberous sclerosis (tsc) 1 (C–D′′), and tsc2 (E–F′′) at stages 35 and 38. Image published in: Romaker D et al. (2014) Copyright © 2014. Image reproduced with permission of the Publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue mtor.L frap, frap1, frap2, LOC108696363, raft1, rapt1, tor X. laevis Throughout NF stage 35 and 36 pronephric kidney head eye pronephric duct ventral blood island lateral plate mesoderm proctodeum spinal cord tail bud myeloid cell tsc1.L hamartin, lam, tsc, tuberous sclerosis 1 X. laevis Throughout NF stage 35 and 36 pronephric kidney head lateral plate mesoderm ventral blood island tsc2.L tuberous sclerosis 2 X. laevis Throughout NF stage 35 and 36 intermediate mesoderm head spinal cord liver mtor.L frap, frap1, frap2, LOC108696363, raft1, rapt1, tor X. laevis Throughout NF stage 37 and 38 pronephric kidney spinal cord ectoderm proximal tubule lateral plate mesoderm head brain pharyngeal region pronephric duct hypaxial muscle tsc1.L hamartin, lam, tsc, tuberous sclerosis 1 X. laevis Throughout NF stage 37 and 38 pronephric kidney proximal tubule hypaxial muscle pharyngeal region head cloaca pronephric duct tsc2.L tuberous sclerosis 2 X. laevis Throughout NF stage 37 and 38 pronephric kidney head spinal cord ectoderm proximal tubule Image source: Published Larger Image Printer Friendly View

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