Xenbase Image ID: 158177

FIGURE 6. The genes involved in tumorigenesis show tissue-specific expression in Xenopus embryos. A, whole mount in situ hybridization (WMISH) detection of expression of genes coding for chromatin modification enzymes. B, WMISH detection of expression of EMT marker genes. Expression of xk81a1 and sox2 is shown as controls. Mid- to late neurula and tailbud embryos were used. Typical expression domains are labeled but the same expression domain in different panels may not be labeled repeatedly. Each embryo is oriented with the anterior to the left. Dorsal view is shown for neurula embryos, and lateral view is shown for tailbud, with dorsal side to the top of each panel. A, anterior; ba, branchial arch; df, dorsal fin; ep, epidermis; ev, ear vesicle; ey, eye; fb, forebrain; hb, hindbrain; he, heart; mb, midbrain; nc, neural crest; np, neural plate; nt, neural tube; P, posterior; pcv, posterior cardinal vein; pl, plexus; pn, pronephros; sc, spinal cord; tb, tailbud. Image published in: Zhang Z et al. (2017) Copyright © 2017. Image reproduced with permission of the Publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue hdac1.L gon-10, hdac1-a, hdac1-b, rpd3, rpd3l1 X. laevis Sometime during NF stage 15 to NF stage 20 neural plate neural crest neural tube hdac3.S HDAC, HDm, Rpd3, XRpd3 X. laevis Sometime during NF stage 15 to NF stage 20 neural plate epidermis neural tube neuroectoderm ectoderm dnmt1.L DNA MeTase, xDnmt1 X. laevis Sometime during NF stage 15 to NF stage 20 neural plate neuroectoderm neural tube ezh2.L enx-1, enx1, ezh1, ezh2-a, ezh2-b, kmt6, xez, xtezh2 X. laevis Sometime during NF stage 15 to NF stage 20 neural plate neuroectoderm neural tube kdm1a.L aof2, kdm1, lsd1, xLSD1 X. laevis Sometime during NF stage 15 to NF stage 20 neural plate neural tube neuroectoderm cdh2.S cadherin-2, cdh2-a, cdh2-b, N-Cad, ncad, N-cadherin X. laevis Sometime during NF stage 15 to NF stage 20 neural plate neural tube neuroectoderm zeb2.S sip1, smad interaction protein 1, XSip1, XZfhx1b, zfhx1b X. laevis Sometime during NF stage 15 to NF stage 20 neural plate neural tube neuroectoderm vim.L vim-a, vim-b, vimentin X. laevis Sometime during NF stage 15 to NF stage 20 neural plate neural tube neuroectoderm ctnnb1.L B-catenin, beta catenin, beta-catenin, ctnnb1-a, ctnnb1-b, β-catenin X. laevis Sometime during NF stage 15 to NF stage 20 neural plate neuroectoderm neural tube sox2.L anop3, LOC108718087, mcops3, Sox-2, XLSOX-2, Xsox-2, XSox2 X. laevis Sometime during NF stage 15 to NF stage 20 neural plate neural tube neuroectoderm snai1.S LOC108702592, sna, snail, snail1, xSna, Xsnail X. laevis Sometime during NF stage 15 to NF stage 20 neural crest cdh1.S arc-1, cd324, cdhe, ecad, e-cadherin, lcam, uvo, uvomorulin, XTCAD-1 X. laevis Sometime during NF stage 15 to NF stage 20 epidermis non-neural ectoderm krt12.4.L ck81, cytok, cytokeratin, E-keratin, epidermal keratin, Epidermis-specific keratin, EpiK, epiker, epi-keratin, epK, EpK, K81, xK81, xk81a, xk81a1 X. laevis Sometime during NF stage 15 to NF stage 20 epidermis non-neural ectoderm hdac1.L gon-10, hdac1-a, hdac1-b, rpd3, rpd3l1 X. laevis Sometime during NF stage 26 to NF stage 32 head region tail bud spinal cord intermediate mesoderm brain eye pharyngeal region central nervous system hdac2.S MGC81850 X. laevis Sometime during NF stage 26 to NF stage 32 forebrain midbrain hindbrain eye otic vesicle central nervous system hdac3.S HDAC, HDm, Rpd3, XRpd3 X. laevis Sometime during NF stage 26 to NF stage 32 branchial arch head region spinal cord otic vesicle brain eye pharyngeal region central nervous system intermediate mesoderm dnmt1.L DNA MeTase, xDnmt1 X. laevis Sometime during NF stage 26 to NF stage 32 intermediate mesoderm head region eye tail bud ezh2.L enx-1, enx1, ezh1, ezh2-a, ezh2-b, kmt6, xez, xtezh2 X. laevis Sometime during NF stage 26 to NF stage 32 head region eye brain pharyngeal region kdm1a.L aof2, kdm1, lsd1, xLSD1 X. laevis Sometime during NF stage 26 to NF stage 32 spinal cord central nervous system eye brain cdh2.S cadherin-2, cdh2-a, cdh2-b, N-Cad, ncad, N-cadherin X. laevis Sometime during NF stage 26 to NF stage 32 forebrain midbrain hindbrain otic vesicle spinal cord tail bud heart eye zeb2.S sip1, smad interaction protein 1, XSip1, XZfhx1b, zfhx1b X. laevis Sometime during NF stage 26 to NF stage 32 pronephric mesenchyme midbrain hindbrain eye spinal cord vim.L vim-a, vim-b, vimentin X. laevis Sometime during NF stage 26 to NF stage 32 head region branchial arch vascular plexus posterior cardinal vein brain central nervous system spinal cord ctnnb1.L B-catenin, beta catenin, beta-catenin, ctnnb1-a, ctnnb1-b, β-catenin X. laevis Sometime during NF stage 26 to NF stage 32 head region tail bud intermediate mesoderm brain ventral tail fin spinal cord otic vesicle eye central nervous system sox2.L anop3, LOC108718087, mcops3, Sox-2, XLSOX-2, Xsox-2, XSox2 X. laevis Sometime during NF stage 26 to NF stage 32 forebrain midbrain hindbrain eye otic vesicle brain snai1.S LOC108702592, sna, snail, snail1, xSna, Xsnail X. laevis Sometime during NF stage 26 to NF stage 32 branchial arch brain pharyngeal region cdh1.S arc-1, cd324, cdhe, ecad, e-cadherin, lcam, uvo, uvomorulin, XTCAD-1 X. laevis Sometime during NF stage 26 to NF stage 32 dorsal fin ventral tail fin epidermis krt12.4.L ck81, cytok, cytokeratin, E-keratin, epidermal keratin, Epidermis-specific keratin, EpiK, epiker, epi-keratin, epK, EpK, K81, xK81, xk81a, xk81a1 X. laevis Sometime during NF stage 26 to NF stage 32 epidermis dorsal fin ventral tail fin eye Image source: Published Larger Image Printer Friendly View

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