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XB-IMG-40717

Xenbase Image ID: 40717


Figure 2. Spatial and temporal expression patterns of VGCC alpha 1 subunits in developing X. laevis embryos using whole-mount in situ hybridization. Embryos were viewed laterally, with anterior to the left and dorsal to the top. A,D,G,J,M,P,S,V,Y: Stages 24-26 (early tail bud). B,E,H,K,N,Q,T,W,Z: Stages 29-31 (late tail bud). C,F,I,L,O,R,U,X,AA: Stages 34-36 (swimming tadpole). A-C: CaV1.1 expression. D-F: CaV1.2 expression. G-I: CaV1.3 expression. J-L: CaV1.4 expression. M-O: CaV2.1 expression. P-R: CaV2.2 expression. S-U: CaV2.3 expression. V-X: CaV3.1 expression. Y-AA: CaV3.2 expression. D prime ,F prime ,S prime ,T prime ,W prime ,Y prime : Magnified images of portions of the embryos indicated by the hollow boxes. AA prime : Magnified image of the tail of an embryo at swimming tadpole stage showing CaV3.2 expression. Arrowheads indicate regions of expression. fb, forebrain; e, eye; hb, hindbrain; ht, heart; mb, midbrain; oe, olfactory epithelium; ot, otic vesicle; pa, pharyngeal arches; pg, pineal gland; sc, spinal cord; so, somite; t, tail bud; V, cranial ganglion V, trigeminal ganglion; VII, cranial ganglion VII, geniculate (facialis) ganglion; IX, cranial ganglion IX, glossopharyngeal ganglion; X, cranial ganglion X, vagal ganglion. Scale bars = 1.0 mm in A-AA, 0.4 mm in AA prime ; 0.2 mm in D prime ,F prime ,S prime ,T prime ,W prime ,Y prime .

Image published in: Lewis BB et al. (2009)

Copyright © 2009. Image reproduced with permission of the Publisher, John Wiley & Sons.

GeneSynonymsSpeciesStage(s)Tissue
cacna1s.Sca(v)1.1, cav1.1, DHPR, alpha sub-unit, LOC108707491X. laevisSometime during NF stage 24 to NF stage 26somite
cacna1c.Sca(v)1.2, cav1.2X. laevisSometime during NF stage 24 to NF stage 26spinal cord
trigeminal nerve
cacna1d.Lca(v)1.3, cav1.3, LOC108704388X. laevisSometime during NF stage 24 to NF stage 26eye
forebrain
pineal gland
heart primordium
hindbrain
midbrain
otic placode
spinal cord
cacna1a.Sca(v)2.1, cav2.1, LOC108710372X. laevisSometime during NF stage 24 to NF stage 26hindbrain
spinal cord
trigeminal nerve
facial nerve
cacna1e.Lca(v)2.3, cav2.3, LOC108715639X. laevisSometime during NF stage 24 to NF stage 26spinal cord
cacna1h.Lca(v)3.2, cav3.2, LOC108702319X. laevisSometime during NF stage 24 to NF stage 26spinal cord
cacna1b.Sbiii, cacnl1a5, cacnn, ca(v)2.2, cav2.2, LOC108699890X. laevisSometime during NF stage 24 to NF stage 26hindbrain
spinal cord
trigeminal nerve
facial nerve
cacna1s.Sca(v)1.1, cav1.1, DHPR, alpha sub-unit, LOC108707491X. laevisSometime during NF stage 29 and 30 to NF stage 31somite
cacna1c.Sca(v)1.2, cav1.2X. laevisSometime during NF stage 29 and 30 to NF stage 31forebrain
hindbrain
midbrain
heart primordium
spinal cord
trigeminal nerve
facial nerve
cacna1d.Lca(v)1.3, cav1.3, LOC108704388X. laevisSometime during NF stage 29 and 30 to NF stage 31eye
forebrain
hindbrain
midbrain
pineal gland
heart primordium
spinal cord
otic vesicle
cacna1a.Sca(v)2.1, cav2.1, LOC108710372X. laevisSometime during NF stage 29 and 30 to NF stage 31forebrain
hindbrain
midbrain
spinal cord
trigeminal nerve
facial nerve
cacna1e.Lca(v)2.3, cav2.3, LOC108715639X. laevisSometime during NF stage 29 and 30 to NF stage 31hindbrain
cacna1g.Lca(v)3.1, cav3.1, LOC108702791X. laevisSometime during NF stage 29 and 30 to NF stage 31pineal gland
hindbrain
spinal cord
otic vesicle
cacna1h.Lca(v)3.2, cav3.2, LOC108702319X. laevisSometime during NF stage 29 and 30 to NF stage 31spinal cord
forebrain
hindbrain
midbrain
heart primordium
cacna1b.Sbiii, cacnl1a5, cacnn, ca(v)2.2, cav2.2, LOC108699890X. laevisSometime during NF stage 29 and 30 to NF stage 31forebrain
hindbrain
midbrain
spinal cord
trigeminal nerve
facial nerve
cacna1c.Sca(v)1.2, cav1.2X. laevisSometime during NF stage 33 and 34 to NF stage 35 and 36eye
forebrain
hindbrain
midbrain
pineal gland
spinal cord
heart
trigeminal nerve
facial nerve
vagus nerve
glossopharyngeal nerve
cacna1d.Lca(v)1.3, cav1.3, LOC108704388X. laevisSometime during NF stage 33 and 34 to NF stage 35 and 36eye
forebrain
hindbrain
midbrain
pineal gland
heart
otic vesicle
spinal cord
cacna1a.Sca(v)2.1, cav2.1, LOC108710372X. laevisSometime during NF stage 33 and 34 to NF stage 35 and 36eye
forebrain
hindbrain
midbrain
spinal cord
trigeminal nerve
vagus nerve
glossopharyngeal nerve
cacna1g.Lca(v)3.1, cav3.1, LOC108702791X. laevisSometime during NF stage 33 and 34 to NF stage 35 and 36eye
forebrain
hindbrain
midbrain
pineal gland
spinal cord
otic vesicle
olfactory epithelial support cell
facial nerve
cacna1h.Lca(v)3.2, cav3.2, LOC108702319X. laevisSometime during NF stage 33 and 34 to NF stage 35 and 36forebrain
heart
hindbrain
midbrain
spinal cord
olfactory epithelial support cell
cacna1f.Lca(v)1.4, cav1.4X. laevisSometime during NF stage 33 and 34 to NF stage 35 and 36eye
cacna1b.Sbiii, cacnl1a5, cacnn, ca(v)2.2, cav2.2, LOC108699890X. laevisSometime during NF stage 33 and 34 to NF stage 35 and 36eye
forebrain
hindbrain
midbrain
spinal cord
trigeminal nerve
vagus nerve
glossopharyngeal nerve
facial nerve
cacna1s.Sca(v)1.1, cav1.1, DHPR, alpha sub-unit, LOC108707491X. laevisSometime during NF stage 33 and 34 to NF stage 35 and 36pharyngeal arch
somite

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