Xenbase Image ID: 46513

Fig. 3. dHAND expression in staged Xenopus embryos. Whole-mount in situ hybridization in Xenopus embryos revealed dHAND expression in punctate subepidermal cells (arrowheads) as early as stage 20 (A). The punctate cells later appeared to be migrating to the branchial arches and heart (C). dHAND expression was observed in the branchial arches throughout their development (C–E). dHAND was expressed bilaterally in the lateral plate mesoderm (lpm) at stage 24 through stage 33 (B–D). High magnification of the anterior embryo better demonstrated expression in the looped heart tube and branchial arches at stage 37 (E). Even higher magnification of the cardiac region (F) demonstrated expression in the heart tube (ht) and outflow tract (ot) at stage 47 without any chamber restriction. Image published in: Angelo S et al. (2000) Copyright © 2000. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue hand2.L dhand, dhand2, hand2-a, hand2-b, xhand2 X. laevis Throughout NF stage 20 epidermis neural crest lateral plate mesoderm cranial neural crest mandibular crest hyoid crest branchial crest cardiac progenitor cell neuroectoderm hand2.L dhand, dhand2, hand2-a, hand2-b, xhand2 X. laevis Throughout NF stage 24 branchial arch heart primordium neural crest mesoderm lateral plate mesoderm pharyngeal arch mandibular arch hyoid arch hand2.L dhand, dhand2, hand2-a, hand2-b, xhand2 X. laevis Throughout NF stage 29 and 30 branchial arch mesoderm heart lateral plate mesoderm heart primordium pharyngeal arch mandibular arch hyoid arch ectoderm hand2.L dhand, dhand2, hand2-a, hand2-b, xhand2 X. laevis Throughout NF stage 33 and 34 lateral plate mesoderm mesoderm heart heart primordium eye pharyngeal arch mandibular arch hyoid arch branchial arch ventral blood island ventral hand2.L dhand, dhand2, hand2-a, hand2-b, xhand2 X. laevis Throughout NF stage 37 and 38 heart branchial arch cardiac mesoderm lateral plate mesoderm pharyngeal arch mandibular arch hyoid arch cardiac ventricle endocardial tube hand2.L dhand, dhand2, hand2-a, hand2-b, xhand2 X. laevis Throughout NF stage 47 heart cardiac mesoderm internal carotid artery external carotid artery cardiac ventricle Image source: Published Larger Image Printer Friendly View

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