Xenbase Image ID: 74569

Figure 5. Expression of HSP60 in regenerating WT and N1 limbs and during development Expression of HSP60 in regenerating WT and N1 limbs and during development. Gene expression in regenerating WT and N1 limbs and embryo tissue. (A-J) In situ hybridisation showing Hsp60 expression in the regeneration bud. (M-P) Unoperated limb buds illustrating Hsp60 expression during limb development. (K) In situ hybridisation showing Hsp60 expression in stage 57 hindlimb of a WT animal 2 days after amputation. (L) In situ hybridisation showing Hsp60 expression in stage 32 embryo. White arrowheads indicate approximate amputation plane, scale bar in A applies to panels A-J and scale bar in P applies to panels M-P. In limb pictures (A-K, M-P) posterior is uppermost, and distal to the left, dr = days of regeneration. In L, anterior is to the left and dorsal uppermost. Image published in: Pearl EJ et al. (2008) Copyright © 2008 Pearl et al; licensee BioMed Central Ltd. Creative Commons Attribution license Gene Synonyms Species Stage(s) Tissue hspd1.S chaperonin, cpn60, GroEL, hld4, hsp60, hsp65, spg13 X. laevis Throughout NF stage 32 pronephric kidney pronephric duct somite trunk somite presomitic mesoderm tail bud pharyngeal arch mandibular arch hyoid arch branchial arch olfactory region lens eye midbrain-hindbrain boundary hspd1.S chaperonin, cpn60, GroEL, hld4, hsp60, hsp65, spg13 X. laevis Sometime during NF stage 52 to NF stage 56 blastema distal mesenchyme Image source: Published Experiment + Assay Source Phenotypes and Disease Xla.Tg(hsp70:nog,cryga:GFP) + hindlimb bud amputation + HS + NF53 Fig. 5 I Expression Phenotype decreased amount hspd1.S expression in apical mesenchyme Xla.Tg(hsp70:nog,cryga:GFP) + hindlimb bud amputation + HS + NF53 Fig. 5 J Expression Phenotype decreased amount hspd1.S expression in apical mesenchyme Larger Image Printer Friendly View

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