Xenbase Image ID: 81668

Figure 2. Ngn3-GR activation affects anterior gut markers at Stage 44. (a) Exocrine pancreatic markers PDI and elastase are slightly decreased (n = 16/16 and n = 14/15, respectively). (e,f) Stomach marker cathepsin E is significantly reduced (n = 14/14). (g,h) Liver and duodenum marker hex is slightly decreased (n = 7/7). Pancreas is outlined in panels (c) and (d). Image published in: Oropeza D and Horb M (2012) Copyright © 2012. Image reproduced with permission of the Publisher, John Wiley & Sons. Gene Synonyms Species Stage(s) Tissue pdia2.L pdi, pdip, XPDIp X. laevis Throughout NF stage 44 foregut pancreas exocrine pancreas cela1.2.L elastase X. laevis Throughout NF stage 44 foregut exocrine pancreas pancreas ctse.L cate, cathepsin E, ce1, ce2, ctse-a, ctse-b X. laevis Throughout NF stage 44 foregut stomach hhex.L hex, tHex, XHex X. laevis Throughout NF stage 44 foregut liver duodenum liver primordium Image source: Published Experiment + Assay Source Phenotypes and Disease Xla Wt + neurog3-GR + DEX + NF44 (in situ hybridization) Fig 2 b Expression Phenotype decreased amount pdia2.L expression in pancreas Xla Wt + neurog3-GR + DEX + NF44 (in situ hybridization) Fig 2 e Expression Phenotype decreased amount ctse.L expression in stomach Xla Wt + neurog3-GR + DEX + NF44 (in situ hybridization) Fig 2 h Expression Phenotype decreased amount hhex.L expression in duodenum decreased amount hhex.L expression in foregut endoderm decreased amount hhex.L expression in liver primordium Larger Image Printer Friendly View

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