Name: Dr. Stephen J Tapscott

Position: Professor of Neurology

Research Description:

Dr. Tapscott's research focuses on genetic regulation of the development of muscle and the nervous system, as well as on molecular mechanisms of genetic muscle disease such as myotonic dystrophy and facioscapulohumeral dystrophy. He and colleagues are interested in determining whether stem cells derived from bone marrow or skeletal muscle can be developed as a possible source of skeletal muscle for the treatment of Duchenne muscular dystrophy.

Current research interests include chromatin structure and the regulation of gene transcription in determining how master regulatory factors drive programs of cell differentiation; the molecular characteristics of neurogenic bHLH proteins in the activation of neural promoters and induction of neurogenesis; chromatin structure and gene expression in facioscapulohumeral and myotonic dystrophy; and the possible use of muscle stem cells in the treatment of Duchenne muscular dystrophy.

Lab Memberships

Tapscott Lab (Principal Investigator/Director)

Contact Information

Address:
Center on Human Development and Disability
University of Washington Medical Center
Seattle, Washington
USA

Web Page: http://depts.washington.edu/chdd/iddrc/res_aff/tapscott.html