Name: Thomas U. Mayer

Research Description:

Our research focuses on mitosis and meiosis in higher eukaryotes. 

Particularly, we are interested in: 

i) how kinesins contribute to chromosome congression in mammalian cells
ii) how anaphase onset is controlled by the ubiquitin/proteasome system
iii) how cytokinesis is synchronized with chromosome segregation.

For these studies we combine molecular and cell biological approaches with biochemistry and live-cell microscopy studies.
In addition to siRNAs, we apply cell-permeable small molecule inhibitors to modulate the activity of proteins in living cells, an approach termed “chemical biology”.

Lab Memberships

Mayer Lab (Principal Investigator/Director)

Contact Information

Address:
Department of Biology and
Konstanz Research School Chemical Biology
University of Konstanz
Universitätsstr. 10
p.o. box M 613
Konstanz
78457, Germany

Web Page: http://www.uni-konstanz.de/thomasmayer/