|
XB-PERS-4941
|
Name: Dr. Nydia Tejeda-Munoz
Position: Wnt signaling in cancer
Research Description:
Our research focuses on understanding the molecular mechanisms that regulate Wnt signaling in cancer, with an emphasis on macropinocytosis and lysosomal function, as well as their interactions with focal adhesions. Key areas of interest include: Investigating how Wnt signaling induces macropinocytosis and how this process contributes to cancer cell growth. Exploring the relationship between Wnt signaling and cellular adhesion and migration in tumor progression and metastasis. Developing novel therapeutic strategies to restore cell adhesion and limit cancer invasiveness by targeting the crosstalk between Wnt signaling and focal adhesions. By targeting endocytosis, macropinocytosis, and lysosomal function, my research seeks to develop novel cancer therapies, particularly for Wnt-driven tumors. Wnt signaling is crucial for regulating cell growth, migration, and differentiation, which are often altered in cancer. Understanding the role of Wnt-induced macropinocytosis in promoting tumor progression could reveal new therapeutic targets. Additionally, my work explores how disrupting lysosomal pathways may impair cancer cells' ability to acquire nutrients, offering potential treatment strategies. Ultimately, I aim to identify molecular approaches that restore healthy cell behavior while limiting cancer invasiveness by modulating key cellular processes.
Lab Memberships
De Robertis Lab
(Post-doc, Alumni)
Contact Information
Address:
Oklahoma City
USA