Name: Joshua M. Brickman

Position: Professor, Group Leader

Research Description:

Mesendoderm is an embryonic tissue that both patterns the anterior-posterior neural axis and gives rise to organs such as the liver and pancreas. Our goal is to understand the mechanism by which sequence specific DNA binding proteins guide early embryo and embryonic stem cell differentiation into mesendoderm. We are particular interested in the developmentally important and relatively non-specific homeodomain transcription factors and the mechanism by which they can induce highly specific responses in both mesendoderm patterning and induction. We seek to understand the mechanism by which these proteins influence the output of specific signalling events to guide key cell fate decisions both in vivo and in vitro.

Lab Memberships

Brickman Lab (Principal Investigator/Director)

Contact Information

Address:
DanStem and CPR
University of Copenhagen
200 København N
Bygning 6.4
Copenhagen
Denmark

Web Page: http://danstem.ku.dk/people/brickman/
Phone:  +45 35 33 51 65