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Chromosomal passenger complex condensates generate parallel microtubule bundles in vitro. , Niedzialkowska E, Truong TM, Eldredge LA, Ali A, Redemann S, Stukenberg PT ., J Biol Chem. March 1, 2024; 300 (3): 105669.
Aurora A phosphorylates Ndel1 to reduce the levels of Mad1 and NuMA at spindle poles. , Janczyk PŁ, Żyłkiewicz E, De Hoyos H, West T, Matson DR, Choi WC, Young HMR, Derewenda ZS, Stukenberg PT ., Mol Biol Cell. January 1, 2023; 34 (1): br1.
High nuclear TPX2 expression correlates with TP53 mutation and poor clinical behavior in a large breast cancer cohort, but is not an independent predictor of chromosomal instability. , Matson DR, Denu RA, Zasadil LM, Burkard ME, Weaver BA, Flynn C, Stukenberg PT ., BMC Cancer. February 23, 2021; 21 (1): 186.
Identification of Drivers of Aneuploidy in Breast Tumors. , Pfister K, Pipka JL, Chiang C, Liu Y , Clark RA, Keller R , Skoglund P , Guertin MJ, Hall IM, Stukenberg PT ., Cell Rep. May 29, 2018; 23 (9): 2758-2769.
Mechanism of Ska Recruitment by Ndc80 Complexes to Kinetochores. , Janczyk PŁ, Skorupka KA, Tooley JG, Matson DR, Kestner CA, West T, Pornillos O, Stukenberg PT ., Dev Cell. May 22, 2017; 41 (4): 438-449.e4.
The Xenopus ORFeome: A resource that enables functional genomics. , Grant IM, Balcha D, Hao T, Shen Y, Trivedi P, Patrushev I , Fortriede JD , Karpinka JB , Liu L, Zorn AM , Stukenberg PT , Hill DE , Gilchrist MJ ., Dev Biol. December 15, 2015; 408 (2): 345-57.
Kif2a depletion generates chromosome segregation and pole coalescence defects in animal caps and inhibits gastrulation of the Xenopus embryo. , Eagleson G , Pfister K, Knowlton AL, Skoglund P , Keller R , Stukenberg PT ., Mol Biol Cell. March 1, 2015; 26 (5): 924-37.
The distinct functions of CENP-C and CENP-T/W in centromere propagation and function in Xenopus egg extracts. , Krizaic I, Williams SJ, Sánchez P, Rodríguez-Corsino M, Stukenberg PT , Losada A., Nucleus. January 1, 2015; 6 (2): 133-43.
EB1 enables spindle microtubules to regulate centromeric recruitment of Aurora B. , Banerjee B, Kestner CA, Stukenberg PT ., J Cell Biol. March 17, 2014; 204 (6): 947-63.
Xenopus egg extracts as a simplified model system for structure-function studies of dynein regulators. , Zyłkiewicz E, Stukenberg PT ., Methods Mol Biol. January 1, 2014; 1136 117-33.
Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres. , Niedzialkowska E, Wang F, Porebski PJ, Minor W, Higgins JM, Stukenberg PT ., Mol Biol Cell. April 1, 2012; 23 (8): 1457-66.
Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling. , Alexander J, Lim D, Joughin BA, Hegemann B, Hutchins JR, Ehrenberger T, Ivins F, Sessa F, Hudecz O, Nigg EA, Fry AM , Musacchio A, Stukenberg PT , Mechtler K, Peters JM , Smerdon SJ, Yaffe MB., Sci Signal. June 28, 2011; 4 (179): ra42.
The N-terminal coiled-coil of Ndel1 is a regulated scaffold that recruits LIS1 to dynein. , Zyłkiewicz E, Kijańska M, Choi WC, Derewenda U, Derewenda ZS, Stukenberg PT ., J Cell Biol. February 7, 2011; 192 (3): 433-45.
Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis. , Wang F, Dai J, Daum JR, Niedzialkowska E, Banerjee B, Stukenberg PT , Gorbsky GJ , Higgins JM., Science. October 8, 2010; 330 (6001): 231-5.
ICIS and Aurora B coregulate the microtubule depolymerase Kif2a. , Knowlton AL, Vorozhko VV, Lan W, Gorbsky GJ , Stukenberg PT ., Curr Biol. May 12, 2009; 19 (9): 758-63.
Perturbation of Incenp function impedes anaphase chromatid movements and chromosomal passenger protein flux at centromeres. , Ahonen LJ, Kukkonen AM, Pouwels J, Bolton MA, Jingle CD, Stukenberg PT , Kallio MJ., Chromosoma. February 1, 2009; 118 (1): 71-84.
Probing kinetochore structure and function using Xenopus laevis frog egg extracts. , Emanuele MJ, Stukenberg PT ., Methods Mol Biol. January 1, 2009; 545 221-32.
Midzone activation of aurora B in anaphase produces an intracellular phosphorylation gradient. , Fuller BG, Lampson MA, Foley EA, Rosasco-Nitcher S, Le KV, Tobelmann P, Brautigan DL, Stukenberg PT , Kapoor TM., Nature. June 19, 2008; 453 (7198): 1132-6.
Aurora B kinase and protein phosphatase 1 have opposing roles in modulating kinetochore assembly. , Emanuele MJ, Lan W, Jwa M, Miller SA, Chan CS, Stukenberg PT ., J Cell Biol. April 21, 2008; 181 (2): 241-54.
Multiple mechanisms of chromosome movement in vertebrate cells mediated through the Ndc80 complex and dynein/dynactin. , Vorozhko VV, Emanuele MJ, Kallio MJ, Stukenberg PT , Gorbsky GJ ., Chromosoma. April 1, 2008; 117 (2): 169-79.
Centromeric Aurora-B activation requires TD-60, microtubules, and substrate priming phosphorylation. , Rosasco-Nitcher SE, Lan W, Khorasanizadeh S, Stukenberg PT ., Science. January 25, 2008; 319 (5862): 469-72.
Xenopus Cep57 is a novel kinetochore component involved in microtubule attachment. , Emanuele MJ, Stukenberg PT ., Cell. September 7, 2007; 130 (5): 893-905.
Aurora B phosphorylates multiple sites on mitotic centromere-associated kinesin to spatially and temporally regulate its function. , Zhang X, Lan W, Ems-McClung SC, Stukenberg PT , Walczak CE., Mol Biol Cell. September 1, 2007; 18 (9): 3264-76.
Regulation of Cdc25C by ERK-MAP kinases during the G2/M transition. , Wang R , He G, Nelman-Gonzalez M, Ashorn CL, Gallick GE, Stukenberg PT , Kirschner MW , Kuang J., Cell. March 23, 2007; 128 (6): 1119-32.
Aurora-A kinase and inhibitor-2 regulate the cyclin threshold for mitotic entry in Xenopus early embryonic cell cycles. , Satinover DL, Brautigan DL, Stukenberg PT ., Cell Cycle. October 1, 2006; 5 (19): 2268-74.
Aurora B is enriched at merotelic attachment sites, where it regulates MCAK. , Knowlton AL, Lan W, Stukenberg PT ., Curr Biol. September 5, 2006; 16 (17): 1705-10.
The reversibility of mitotic exit in vertebrate cells. , Potapova TA, Daum JR, Pittman BD, Hudson JR, Jones TN, Satinover DL, Stukenberg PT , Gorbsky GJ ., Nature. April 13, 2006; 440 (7086): 954-8.
Measuring the stoichiometry and physical interactions between components elucidates the architecture of the vertebrate kinetochore. , Emanuele MJ, McCleland ML, Satinover DL, Stukenberg PT ., Mol Biol Cell. October 1, 2005; 16 (10): 4882-92.
Polo-like kinase 1 creates the tension-sensing 3F3/2 phosphoepitope and modulates the association of spindle-checkpoint proteins at kinetochores. , Ahonen LJ, Kallio MJ, Daum JR, Bolton M, Manke IA, Yaffe MB, Stukenberg PT , Gorbsky GJ ., Curr Biol. June 21, 2005; 15 (12): 1078-89.
Mechanism of Aurora B activation by INCENP and inhibition by hesperadin. , Sessa F, Mapelli M, Ciferri C, Tarricone C, Areces LB, Schneider TR, Stukenberg PT , Musacchio A., Mol Cell. April 29, 2005; 18 (3): 379-91.
Purification of the Ndc80 kinetochore subcomplex from Xenopus eggs. , McCleland ML, Stukenberg PT ., Methods Mol Biol. January 1, 2005; 296 383-91.
Activation of Aurora-A kinase by protein phosphatase inhibitor-2, a bifunctional signaling protein. , Satinover DL, Leach CA, Stukenberg PT , Brautigan DL., Proc Natl Acad Sci U S A. June 8, 2004; 101 (23): 8625-30.
Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activity. , Lan W, Zhang X, Kline-Smith SL, Rosasco SE, Barrett-Wilt GA, Shabanowitz J, Hunt DF, Walczak CE, Stukenberg PT ., Curr Biol. February 17, 2004; 14 (4): 273-86.
The vertebrate Ndc80 complex contains Spc24 and Spc25 homologs, which are required to establish and maintain kinetochore- microtubule attachment. , McCleland ML, Kallio MJ, Barrett-Wilt GA, Kestner CA, Shabanowitz J, Hunt DF, Gorbsky GJ , Stukenberg PT ., Curr Biol. January 20, 2004; 14 (2): 131-7.
Analyzing the spindle checkpoint in yeast and frogs. , Stukenberg PT , Burke DJ., Methods Mol Biol. January 1, 2004; 280 83-98.
The quest for the holy "G" of chromosomal passengers. , Burke DJ, Stukenberg PT ., Dev Cell. August 1, 2003; 5 (2): 187-8.
The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity. , McCleland ML, Gardner RD, Kallio MJ, Daum JR, Gorbsky GJ , Burke DJ, Stukenberg PT ., Genes Dev. January 1, 2003; 17 (1): 101-14.
Aurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and phosphorylation. , Bolton MA, Lan W, Powers SE, McCleland ML, Kuang J, Stukenberg PT ., Mol Biol Cell. September 1, 2002; 13 (9): 3064-77.
Inhibition of aurora B kinase blocks chromosome segregation, overrides the spindle checkpoint, and perturbs microtubule dynamics in mitosis. , Kallio MJ, McCleland ML, Stukenberg PT , Gorbsky GJ ., Curr Biol. June 4, 2002; 12 (11): 900-5.
The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinase. , Sumara I, Vorlaufer E, Stukenberg PT , Kelm O, Redemann N, Nigg EA, Peters JM ., Mol Cell. March 1, 2002; 9 (3): 515-25.
Timing of events in mitosis. , Georgi AB, Stukenberg PT , Kirschner MW ., Curr Biol. January 22, 2002; 12 (2): 105-14.
A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization. , Du Q, Stukenberg PT , Macara IG., Nat Cell Biol. December 1, 2001; 3 (12): 1069-75.
Pin1 acts catalytically to promote a conformational change in Cdc25. , Stukenberg PT , Kirschner MW ., Mol Cell. May 1, 2001; 7 (5): 1071-83.
LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome. , Feng Y, Olson EC, Stukenberg PT , Flanagan LA, Kirschner MW , Walsh CA., Neuron. December 1, 2000; 28 (3): 665-79.
Cell cycle-regulated phosphorylation of the human SIX1 homeodomain protein. , Ford HL, Landesman-Bollag E, Dacwag CS, Stukenberg PT , Pardee AB, Seldin DC., J Biol Chem. July 21, 2000; 275 (29): 22245-54.
The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins. , Shen M, Stukenberg PT , Kirschner MW , Lu KP., Genes Dev. March 1, 1998; 12 (5): 706-20.
Systematic identification of mitotic phosphoproteins. , Stukenberg PT , Lustig KD , McGarry TJ, King RW, Kuang J, Kirschner MW ., Curr Biol. May 1, 1997; 7 (5): 338-48.
Small pool expression screening: identification of genes involved in cell cycle control, apoptosis, and early development. , Lustig KD , Stukenberg PT , McGarry TJ, King RW, Cryns VL, Mead PE , Zon LI , Yuan J, Kirschner MW ., Methods Enzymol. January 1, 1997; 283 83-99.