Isabel Dominguez - Publications

Publications (23)

XB-PERS-1884

Publications By Isabel Dominguez

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GPCR-independent activation of G proteins promotes apical cell constriction in vivo., Marivin A, Morozova V, Walawalkar I, Leyme A, Kretov DA, Cifuentes D, Dominguez I, Garcia-Marcos M., J Cell Biol. May 6, 2019; 218 (5): 1743-1763.
Specific inhibition of GPCR-independent G protein signaling by a rationally engineered protein., Leyme A, Marivin A, Maziarz M, DiGiacomo V, Papakonstantinou MP, Patel PP, Blanco-Canosa JB, Walawalkar IA, Rodriguez-Davila G, Dominguez I, Garcia-Marcos M., Proc Natl Acad Sci U S A. November 28, 2017; 114 (48): E10319-E10328.
Dominant-negative Gα subunits are a mechanism of dysregulated heterotrimeric G protein signaling in human disease., Marivin A, Leyme A, Parag-Sharma K, DiGiacomo V, Cheung AY, Nguyen LT, Dominguez I, Garcia-Marcos M., Sci Signal. April 12, 2016; 9 (423): ra37.
Asymmetric Localization of CK2α During Xenopus Oogenesis., Imbrie GA, Wu H, Seldin DC, Dominguez I., Hum Genet Embryol. May 5, 2012; Suppl 4 (1): 11328.
Threonine 393 of beta-catenin regulates interaction with Axin., Wu H, Symes K, Seldin DC, Dominguez I., J Cell Biochem. September 1, 2009; 108 (1): 52-63.
Beta-arrestin and casein kinase 1/2 define distinct branches of non-canonical WNT signalling pathways., Bryja V, Schambony A, Cajánek L, Dominguez I, Arenas E, Schulte G., EMBO Rep. December 1, 2008; 9 (12): 1244-50.
Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL., Chitalia VC, Foy RL, Bachschmid MM, Zeng L, Panchenko MV, Zhou MI, Bharti A, Seldin DC, Lecker SH, Dominguez I, Cohen HT., Nat Cell Biol. October 1, 2008; 10 (10): 1208-16.
A role for CK2alpha/beta in Xenopus early embryonic development., Dominguez I, Mizuno J, Wu H, Imbrie GA, Symes K, Seldin DC., Mol Cell Biochem. June 1, 2005; 274 (1-2): 125-31.
Self-organization of vertebrate mesoderm based on simple boundary conditions., Green JB, Dominguez I, Davidson LA., Dev Dyn. November 1, 2004; 231 (3): 576-81.
Protein kinase CK2 is required for dorsal axis formation in Xenopus embryos., Dominguez I, Mizuno J, Wu H, Song DH, Symes K, Seldin DC., Dev Biol. October 1, 2004; 274 (1): 110-24.
CK2 phosphorylation of the armadillo repeat region of beta-catenin potentiates Wnt signaling., Song DH, Dominguez I, Mizuno J, Kaut M, Mohr SC, Seldin DC., J Biol Chem. June 27, 2003; 278 (26): 24018-25.
Missing links in GSK3 regulation., Dominguez I, Green JB., Dev Biol. July 15, 2001; 235 (2): 303-13.
Dorsal downregulation of GSK3beta by a non-Wnt-like mechanism is an early molecular consequence of cortical rotation in early Xenopus embryos., Dominguez I, Green JB., Development. February 1, 2000; 127 (4): 861-8.
Role of glycogen synthase kinase 3 beta as a negative regulator of dorsoventral axis formation in Xenopus embryos., Dominguez I, Itoh K, Sokol SY., Proc Natl Acad Sci U S A. August 29, 1995; 92 (18): 8498-502.
Protein kinase C zeta isoform is critical for kappa B-dependent promoter activation by sphingomyelinase., Lozano J, Berra E, Municio MM, Diaz-Meco MT, Dominguez I, Sanz L, Moscat J., J Biol Chem. July 29, 1994; 269 (30): 19200-2.
zeta PKC induces phosphorylation and inactivation of I kappa B-alpha in vitro., Diaz-Meco MT, Dominguez I, Sanz L, Dent P, Lozano J, Municio MM, Berra E, Hay RT, Sturgill TW, Moscat J., EMBO J. June 15, 1994; 13 (12): 2842-8.
Protein kinase C zeta isoform is critical for mitogenic signal transduction., Berra E, Diaz-Meco MT, Dominguez I, Municio MM, Sanz L, Lozano J, Chapkin RS, Moscat J., Cell. August 13, 1993; 74 (3): 555-63.
A dominant negative protein kinase C zeta subspecies blocks NF-kappa B activation., Diaz-Meco MT, Berra E, Municio MM, Sanz L, Lozano J, Dominguez I, Diaz-Golpe V, Lain de Lera MT, Alcamí J, Payá CV, Arenzana-Seisedos F, Virelizier JL, Moscat J., Mol Cell Biol. August 1, 1993; 13 (8): 4770-5.
Inhibition of protein kinase C zeta subspecies blocks the activation of an NF-kappa B-like activity in Xenopus laevis oocytes., Dominguez I, Sanz L, Arenzana-Seisdedos F, Diaz-Meco MT, Virelizier JL, Moscat J., Mol Cell Biol. February 1, 1993; 13 (2): 1290-5.
Evidence for a role of protein kinase C zeta subspecies in maturation of Xenopus laevis oocytes., Dominguez I, Diaz-Meco MT, Municio MM, Berra E, García de Herreros A, Cornet ME, Sanz L, Moscat J., Mol Cell Biol. September 1, 1992; 12 (9): 3776-83.
Phospholipase C-mediated hydrolysis of phosphatidylcholine is a target of transforming growth factor beta 1 inhibitory signals., Diaz-Meco MT, Dominguez I, Sanz L, Municio MM, Berra E, Cornet ME, Garcia de Herreros A, Johansen T, Moscat J., Mol Cell Biol. January 1, 1992; 12 (1): 302-8.
Role of GTPase activating protein in mitogenic signalling through phosphatidylcholine-hydrolysing phospholipase C., Dominguez I, Marshall MS, Gibbs JB, García de Herreros A, Cornet ME, Graziani G, Diaz-Meco MT, Johansen T, McCormick F, Moscat J., EMBO J. November 1, 1991; 10 (11): 3215-20.
Requirement of phospholipase C-catalyzed hydrolysis of phosphatidylcholine for maturation of Xenopus laevis oocytes in response to insulin and ras p21., García de Herreros A, Dominguez I, Diaz-Meco MT, Graziani G, Cornett ME, Guddal PH, Johansen T, Moscat J., J Biol Chem. April 15, 1991; 266 (11): 6825-9.

GPCR-independent activation of G proteins promotes apical cell constriction in vivo., Marivin A, Morozova V, Walawalkar I, Leyme A, Kretov DA, Cifuentes D, Dominguez I, Garcia-Marcos M., J Cell Biol. May 6, 2019; 218 (5): 1743-1763.

Specific inhibition of GPCR-independent G protein signaling by a rationally engineered protein., Leyme A, Marivin A, Maziarz M, DiGiacomo V, Papakonstantinou MP, Patel PP, Blanco-Canosa JB, Walawalkar IA, Rodriguez-Davila G, Dominguez I, Garcia-Marcos M., Proc Natl Acad Sci U S A. November 28, 2017; 114 (48): E10319-E10328.

Dominant-negative Gα subunits are a mechanism of dysregulated heterotrimeric G protein signaling in human disease., Marivin A, Leyme A, Parag-Sharma K, DiGiacomo V, Cheung AY, Nguyen LT, Dominguez I, Garcia-Marcos M., Sci Signal. April 12, 2016; 9 (423): ra37.

Asymmetric Localization of CK2α During Xenopus Oogenesis., Imbrie GA, Wu H, Seldin DC, Dominguez I., Hum Genet Embryol. May 5, 2012; Suppl 4 (1): 11328.

Threonine 393 of beta-catenin regulates interaction with Axin., Wu H, Symes K, Seldin DC, Dominguez I., J Cell Biochem. September 1, 2009; 108 (1): 52-63.

Beta-arrestin and casein kinase 1/2 define distinct branches of non-canonical WNT signalling pathways., Bryja V, Schambony A, Cajánek L, Dominguez I, Arenas E, Schulte G., EMBO Rep. December 1, 2008; 9 (12): 1244-50.

Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL., Chitalia VC, Foy RL, Bachschmid MM, Zeng L, Panchenko MV, Zhou MI, Bharti A, Seldin DC, Lecker SH, Dominguez I, Cohen HT., Nat Cell Biol. October 1, 2008; 10 (10): 1208-16.

A role for CK2alpha/beta in Xenopus early embryonic development., Dominguez I, Mizuno J, Wu H, Imbrie GA, Symes K, Seldin DC., Mol Cell Biochem. June 1, 2005; 274 (1-2): 125-31.

Self-organization of vertebrate mesoderm based on simple boundary conditions., Green JB, Dominguez I, Davidson LA., Dev Dyn. November 1, 2004; 231 (3): 576-81.

Protein kinase CK2 is required for dorsal axis formation in Xenopus embryos., Dominguez I, Mizuno J, Wu H, Song DH, Symes K, Seldin DC., Dev Biol. October 1, 2004; 274 (1): 110-24.

CK2 phosphorylation of the armadillo repeat region of beta-catenin potentiates Wnt signaling., Song DH, Dominguez I, Mizuno J, Kaut M, Mohr SC, Seldin DC., J Biol Chem. June 27, 2003; 278 (26): 24018-25.

Missing links in GSK3 regulation., Dominguez I, Green JB., Dev Biol. July 15, 2001; 235 (2): 303-13.

Dorsal downregulation of GSK3beta by a non-Wnt-like mechanism is an early molecular consequence of cortical rotation in early Xenopus embryos., Dominguez I, Green JB., Development. February 1, 2000; 127 (4): 861-8.

Role of glycogen synthase kinase 3 beta as a negative regulator of dorsoventral axis formation in Xenopus embryos., Dominguez I, Itoh K, Sokol SY., Proc Natl Acad Sci U S A. August 29, 1995; 92 (18): 8498-502.

Protein kinase C zeta isoform is critical for kappa B-dependent promoter activation by sphingomyelinase., Lozano J, Berra E, Municio MM, Diaz-Meco MT, Dominguez I, Sanz L, Moscat J., J Biol Chem. July 29, 1994; 269 (30): 19200-2.

zeta PKC induces phosphorylation and inactivation of I kappa B-alpha in vitro., Diaz-Meco MT, Dominguez I, Sanz L, Dent P, Lozano J, Municio MM, Berra E, Hay RT, Sturgill TW, Moscat J., EMBO J. June 15, 1994; 13 (12): 2842-8.

Protein kinase C zeta isoform is critical for mitogenic signal transduction., Berra E, Diaz-Meco MT, Dominguez I, Municio MM, Sanz L, Lozano J, Chapkin RS, Moscat J., Cell. August 13, 1993; 74 (3): 555-63.

A dominant negative protein kinase C zeta subspecies blocks NF-kappa B activation., Diaz-Meco MT, Berra E, Municio MM, Sanz L, Lozano J, Dominguez I, Diaz-Golpe V, Lain de Lera MT, Alcamí J, Payá CV, Arenzana-Seisedos F, Virelizier JL, Moscat J., Mol Cell Biol. August 1, 1993; 13 (8): 4770-5.

Inhibition of protein kinase C zeta subspecies blocks the activation of an NF-kappa B-like activity in Xenopus laevis oocytes., Dominguez I, Sanz L, Arenzana-Seisdedos F, Diaz-Meco MT, Virelizier JL, Moscat J., Mol Cell Biol. February 1, 1993; 13 (2): 1290-5.

Evidence for a role of protein kinase C zeta subspecies in maturation of Xenopus laevis oocytes., Dominguez I, Diaz-Meco MT, Municio MM, Berra E, García de Herreros A, Cornet ME, Sanz L, Moscat J., Mol Cell Biol. September 1, 1992; 12 (9): 3776-83.

Phospholipase C-mediated hydrolysis of phosphatidylcholine is a target of transforming growth factor beta 1 inhibitory signals., Diaz-Meco MT, Dominguez I, Sanz L, Municio MM, Berra E, Cornet ME, Garcia de Herreros A, Johansen T, Moscat J., Mol Cell Biol. January 1, 1992; 12 (1): 302-8.

Role of GTPase activating protein in mitogenic signalling through phosphatidylcholine-hydrolysing phospholipase C., Dominguez I, Marshall MS, Gibbs JB, García de Herreros A, Cornet ME, Graziani G, Diaz-Meco MT, Johansen T, McCormick F, Moscat J., EMBO J. November 1, 1991; 10 (11): 3215-20.

Requirement of phospholipase C-catalyzed hydrolysis of phosphatidylcholine for maturation of Xenopus laevis oocytes in response to insulin and ras p21., García de Herreros A, Dominguez I, Diaz-Meco MT, Graziani G, Cornett ME, Guddal PH, Johansen T, Moscat J., J Biol Chem. April 15, 1991; 266 (11): 6825-9.

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