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The Atad5 RFC-like complex is the major unloader of proliferating cell nuclear antigen in Xenopus egg extracts. , Kawasoe Y, Shimokawa S, Gillespie PJ, Blow JJ , Tsurimoto T, Takahashi TS., J Biol Chem. January 21, 2023; 300 (1): 105588.
The role of DDK and Treslin- MTBP in coordinating replication licensing and pre-initiation complex formation. , Volpi I, Gillespie PJ, Chadha GS, Blow JJ ., Open Biol. October 1, 2021; 11 (10): 210121.
The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines. , Gardner NJ, Gillespie PJ, Carrington JT, Shanks EJ, McElroy SP, Haagensen EJ, Frearson JA, Woodland A, Blow JJ ., Cell Chem Biol. August 17, 2017; 24 (8): 981-992.e4.
Reversal of DDK-Mediated MCM Phosphorylation by Rif1- PP1 Regulates Replication Initiation and Replisome Stability Independently of ATR/ Chk1. , Alver RC, Chadha GS, Gillespie PJ, Blow JJ ., Cell Rep. March 7, 2017; 18 (10): 2508-2520.
Xenopus Mcm10 is a CDK-substrate required for replication fork stability. , Chadha GS, Gambus A, Gillespie PJ, Blow JJ ., Cell Cycle. August 17, 2016; 15 (16): 2183-2195.
Direct non transcriptional role of NF-Y in DNA replication. , Benatti P, Belluti S, Miotto B, Neusiedler J, Dolfini D, Drac M, Basile V, Schwob E, Mantovani R, Blow JJ , Imbriano C., Biochim Biophys Acta. April 1, 2016; 1863 (4): 673-85.
Cell Cycle Synchronization in Xenopus Egg Extracts. , Gillespie PJ, Neusiedler J, Creavin K, Chadha GS, Blow JJ ., Methods Mol Biol. January 1, 2016; 1342 101-47.
Xenopus cell-free extracts and their contribution to the study of DNA replication and other complex biological processes. , Blow JJ , Laskey RA., Int J Dev Biol. January 1, 2016; 60 (7-8-9): 201-207.
Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1. , Poh WT, Chadha GS, Gillespie PJ, Kaldis P, Blow JJ ., Open Biol. January 8, 2014; 4 (1): 130138.
The Geminin and Idas coiled coils preferentially form a heterodimer that inhibits Geminin function in DNA replication licensing. , Caillat C, Pefani DE, Gillespie PJ, Taraviras S, Blow JJ , Lygerou Z, Perrakis A., J Biol Chem. November 1, 2013; 288 (44): 31624-34.
Mcm8 and Mcm9 form a dimeric complex in Xenopus laevis egg extract that is not essential for DNA replication initiation. , Gambus A, Blow JJ ., Cell Cycle. April 15, 2013; 12 (8): 1225-32.
Preparation and use of Xenopus egg extracts to study DNA replication and chromatin associated proteins. , Gillespie PJ, Gambus A, Blow JJ ., Methods. June 1, 2012; 57 (2): 203-13.
Optimal placement of origins for DNA replication. , Karschau J, Blow JJ , de Moura AP., Phys Rev Lett. February 3, 2012; 108 (5): 058101.
Dynamic interactions of high Cdt1 and geminin levels regulate S phase in early Xenopus embryos. , Kisielewska J , Blow JJ ., Development. January 1, 2012; 139 (1): 63-74.
CDC-48/ p97 coordinates CDT-1 degradation with GINS chromatin dissociation to ensure faithful DNA replication. , Franz A, Orth M, Pirson PA, Sonneville R, Blow JJ , Gartner A, Stemmann O, Hoppe T., Mol Cell. October 7, 2011; 44 (1): 85-96.
Biphasic chromatin binding of histone chaperone FACT during eukaryotic chromatin DNA replication. , Kundu LR, Seki M, Watanabe N, Murofushi H, Furukohri A, Waga S, Score AJ, Blow JJ , Horikoshi M, Enomoto T, Tada S., Biochim Biophys Acta. June 1, 2011; 1813 (6): 1129-36.
MCM2-7 form double hexamers at licensed origins in Xenopus egg extract. , Gambus A, Khoudoli GA, Jones RC, Blow JJ ., J Biol Chem. April 1, 2011; 286 (13): 11855-64.
Evidence for a mammalian late-G1 phase inhibitor of replication licensing distinct from geminin or Cdk activity. , Sasaki T, Li A, Gillespie PJ, Blow JJ , Gilbert DM., Nucleus. January 1, 2011; 2 (5): 455-64.
Clusters, factories and domains: The complex structure of S-phase comes into focus. , Gillespie PJ, Blow JJ ., Cell Cycle. August 15, 2010; 9 (16): 3218-26.
Replication factory activation can be decoupled from the replication timing program by modulating Cdk levels. , Thomson AM, Gillespie PJ, Blow JJ ., J Cell Biol. January 25, 2010; 188 (2): 209-21.
Quaternary structure of the human Cdt1- Geminin complex regulates DNA replication licensing. , De Marco V, Gillespie PJ, Li A, Karantzelis N, Christodoulou E, Klompmaker R, van Gerwen S, Fish A, Petoukhov MV, Iliou MS, Lygerou Z, Medema RH, Blow JJ , Svergun DI, Taraviras S, Perrakis A., Proc Natl Acad Sci U S A. November 24, 2009; 106 (47): 19807-12.
Rapid induction of pluripotency genes after exposure of human somatic cells to mouse ES cell extracts. , Bru T, Clarke C, McGrew MJ, Sang HM, Wilmut I, Blow JJ ., Exp Cell Res. August 15, 2008; 314 (14): 2634-42.
Temporal profiling of the chromatin proteome reveals system-wide responses to replication inhibition. , Khoudoli GA, Gillespie PJ, Stewart G, Andersen JS, Swedlow JR, Blow JJ ., Curr Biol. June 3, 2008; 18 (11): 838-43.
PTIP/ Swift is required for efficient PCNA ubiquitination in response to DNA damage. , Göhler T, Munoz IM, Rouse J, Blow JJ ., DNA Repair (Amst). May 3, 2008; 7 (5): 775-87.
Bod1, a novel kinetochore protein required for chromosome biorientation. , Porter IM, McClelland SE, Khoudoli GA, Hunter CJ, Andersen JS, McAinsh AD, Blow JJ , Swedlow JR., J Cell Biol. October 22, 2007; 179 (2): 187-97.
ELYS/MEL-28 chromatin association coordinates nuclear pore complex assembly and replication licensing. , Gillespie PJ, Khoudoli GA, Stewart G, Swedlow JR, Blow JJ ., Curr Biol. October 9, 2007; 17 (19): 1657-62.
The elusive determinants of replication origins. , Costa S, Blow JJ ., EMBO Rep. April 1, 2007; 8 (4): 332-4.
Deregulated replication licensing causes DNA fragmentation consistent with head-to- tail fork collision. , Davidson IF, Li A, Blow JJ ., Mol Cell. November 3, 2006; 24 (3): 433-43.
Excess Mcm2-7 license dormant origins of replication that can be used under conditions of replicative stress. , Woodward AM, Göhler T, Luciani MG, Oehlmann M, Ge X, Gartner A, Jackson DA, Blow JJ ., J Cell Biol. June 5, 2006; 173 (5): 673-83.
Cdt1 downregulation by proteolysis and geminin inhibition prevents DNA re-replication in Xenopus. , Li A, Blow JJ ., EMBO J. January 26, 2005; 24 (2): 395-404.
Functional domains of the Xenopus replication licensing factor Cdt1. , Ferenbach A, Li A, Brito-Martins M, Blow JJ ., Nucleic Acids Res. January 12, 2005; 33 (1): 316-24.
Characterization of a novel ATR-dependent, Chk1-independent, intra-S-phase checkpoint that suppresses initiation of replication in Xenopus. , Luciani MG, Oehlmann M, Blow JJ ., J Cell Sci. December 1, 2004; 117 (Pt 25): 6019-30.
DNA replication licensing in somatic and germ cells. , Eward KL, Obermann EC, Shreeram S, Loddo M, Fanshawe T, Williams C, Jung HI , Prevost AT, Blow JJ , Stoeber K, Williams GH., J Cell Sci. November 15, 2004; 117 (Pt 24): 5875-86.
A Xenopus Dbf4 homolog is required for Cdc7 chromatin binding and DNA replication. , Jares P, Luciani MG, Blow JJ ., BMC Mol Biol. June 28, 2004; 5 5.
The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activation. , Oehlmann M, Score AJ, Blow JJ ., J Cell Biol. April 26, 2004; 165 (2): 181-90.
Negative regulation of geminin by CDK-dependent ubiquitination controls replication licensing. , Li A, Blow JJ ., Cell Cycle. April 1, 2004; 3 (4): 443-5.
Non-proteolytic inactivation of geminin requires CDK-dependent ubiquitination. , Li A, Blow JJ ., Nat Cell Biol. March 1, 2004; 6 (3): 260-7.
Geminin becomes activated as an inhibitor of Cdt1/RLF-B following nuclear import. , Hodgson B, Li A, Tada S, Blow JJ ., Curr Biol. April 16, 2002; 12 (8): 678-83.
Mammalian nuclei become licensed for DNA replication during late telophase. , Dimitrova DS, Prokhorova TA, Blow JJ , Todorov IT, Gilbert DM., J Cell Sci. January 1, 2002; 115 (Pt 1): 51-9.
Control of chromosomal DNA replication in the early Xenopus embryo. , Blow JJ ., EMBO J. July 2, 2001; 20 (13): 3293-7.
Use of peptides from p21 (Waf1/ Cip1) to investigate PCNA function in Xenopus egg extracts. , Mattock H, Jares P, Zheleva DI, Lane DP, Warbrick E, Blow JJ ., Exp Cell Res. May 1, 2001; 265 (2): 242-51.
Repression of origin assembly in metaphase depends on inhibition of RLF-B/ Cdt1 by geminin. , Tada S, Li A, Maiorano D , Méchali M, Blow JJ ., Nat Cell Biol. February 1, 2001; 3 (2): 107-13.
Replication origins in Xenopus egg extract Are 5-15 kilobases apart and are activated in clusters that fire at different times. , Blow JJ , Gillespie PJ, Francis D, Jackson DA., J Cell Biol. January 8, 2001; 152 (1): 15-25.
Reconstitution of licensed replication origins on Xenopus sperm nuclei using purified proteins. , Gillespie PJ, Li A, Blow JJ ., BMC Biochem. January 1, 2001; 2 15.
Xenopus cdc7 function is dependent on licensing but not on XORC, XCdc6, or CDK activity and is required for XCdc45 loading. , Jares P, Blow JJ ., Genes Dev. June 15, 2000; 14 (12): 1528-40.
Cell cycle. A new check on issuing the licence. , Blow JJ , Tada S., Nature. April 6, 2000; 404 (6778): 560-1.
Interaction of Xenopus Cdc2 x cyclin A1 with the origin recognition complex. , Romanowski P, Marr J, Madine MA, Rowles A , Blow JJ , Gautier J , Laskey RA., J Biol Chem. February 11, 2000; 275 (6): 4239-43.
The replication capacity of intact mammalian nuclei in Xenopus egg extracts declines with quiescence, but the residual DNA synthesis is independent of Xenopus MCM proteins. , Sun W, Hola M, Pedley K, Tada S, Blow JJ , Todorov IT, Kearsey SE, Brooks RF., J Cell Sci. February 1, 2000; 113 ( Pt 4) 683-95.
Sequential MCM/ P1 subcomplex assembly is required to form a heterohexamer with replication licensing activity. , Prokhorova TA, Blow JJ ., J Biol Chem. January 28, 2000; 275 (4): 2491-8.
Nucleoplasmin-mediated chromatin remodelling is required for Xenopus sperm nuclei to become licensed for DNA replication. , Gillespie PJ, Blow JJ ., Nucleic Acids Res. January 15, 2000; 28 (2): 472-80.