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A Modified Tripeptide Motif of RS1 ( RSC1A1) Down-Regulates Exocytotic Pathways of Human Na+-d-glucose Cotransporters SGLT1, SGLT2, and Glucose Sensor SGLT3 in the Presence of Glucose. , Schäfer N, Rikkala PR, Veyhl-Wichmann M, Keller T , Jurowich CF, Geiger D, Koepsell H., Mol Pharmacol. January 1, 2019; 95 (1): 82-96.
Protein RS1 ( RSC1A1) Downregulates the Exocytotic Pathway of Glucose Transporter SGLT1 at Low Intracellular Glucose via Inhibition of Ornithine Decarboxylase. , Chintalapati C, Keller T , Mueller TD, Gorboulev V, Schäfer N, Zilkowski I, Veyhl-Wichmann M, Geiger D, Groll J, Koepsell H., Mol Pharmacol. November 1, 2016; 90 (5): 508-521.
Phosphorylation of RS1 ( RSC1A1) Steers Inhibition of Different Exocytotic Pathways for Glucose Transporter SGLT1 and Nucleoside Transporter CNT1, and an RS1-Derived Peptide Inhibits Glucose Absorption. , Veyhl-Wichmann M, Friedrich A, Vernaleken A, Singh S, Kipp H, Gorboulev V, Keller T , Chintalapati C, Pipkorn R, Pastor-Anglada M, Groll J, Koepsell H., Mol Pharmacol. January 1, 2016; 89 (1): 118-32.
A substrate binding hinge domain is critical for transport-related structural changes of organic cation transporter 1. , Egenberger B, Gorboulev V, Keller T , Gorbunov D, Gottlieb N, Geiger D, Mueller TD, Koepsell H., J Biol Chem. September 7, 2012; 287 (37): 31561-73.
The large extracellular loop of organic cation transporter 1 influences substrate affinity and is pivotal for oligomerization. , Keller T , Egenberger B, Gorboulev V, Bernhard F, Uzelac Z, Gorbunov D, Wirth C, Koppatz S, Dötsch V, Hunte C, Sitte HH, Koepsell H., J Biol Chem. October 28, 2011; 286 (43): 37874-86.
Identification of cysteines in rat organic cation transporters rOCT1 (C322, C451) and rOCT2 (C451) critical for transport activity and substrate affinity. , Sturm A, Gorboulev V, Gorbunov D, Keller T , Volk C, Schmitt BM, Schlachtbauer P, Ciarimboli G, Koepsell H., Am J Physiol Renal Physiol. September 1, 2007; 293 (3): F767-79.
Endogenous patterns of TGFbeta superfamily signaling during early Xenopus development. , Faure S , Lee MA, Keller T , ten Dijke P, Whitman M ., Development. July 1, 2000; 127 (13): 2917-31.