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Using Xenopus to discover new candidate genes involved in BOR and other congenital hearing loss syndromes. , Neal SJ, Rajasekaran A, Jusić N, Taylor L , Read M, Alfandari D , Pignoni F, Moody SA ., J Exp Zool B Mol Dev Evol. May 1, 2024; 342 (3): 212-240.
Production and characterization of monoclonal antibodies to Xenopus proteins. , Horr B, Kurtz R, Pandey A, Hoffstrom BG, Schock E , LaBonne C , Alfandari D ., Development. February 15, 2023; 150 (4):
Production and characterization of monoclonal antibodies to xenopus proteins. , Horr B, Kurtz R, Pandey A, Hoffstrom BG, Schock E , LaBonne C , Alfandari D ., Development. February 14, 2023;
ADAM11 a novel regulator of Wnt and BMP4 signaling in neural crest and cancer. , Pandey A, Cousin H , Horr B, Alfandari D ., Front Cell Dev Biol. January 1, 2023; 11 1271178.
Zmym4 is required for early cranial gene expression and craniofacial cartilage formation. , Jourdeuil K, Neilson KM , Cousin H , Tavares ALP, Majumdar HD, Alfandari D , Moody SA ., Front Cell Dev Biol. January 1, 2023; 11 1274788.
Trim-Away mediated knock down uncovers a new function for Lbh during gastrulation of Xenopus laevis. , Weir E, McLinden G, Alfandari D , Cousin H ., Dev Biol. February 1, 2021; 470 74-83.
Mcrs1 interacts with Six1 to influence early craniofacial and otic development. , Neilson KM , Keer S, Bousquet N, Macrorie O, Majumdar HD, Kenyon KL , Alfandari D , Moody SA ., Dev Biol. November 1, 2020; 467 (1-2): 39-50.
Endoplasmic reticulum transmembrane protein TMTC3 contributes to O-mannosylation of E-cadherin, cellular adherence, and embryonic gastrulation. , Graham JB, Sunryd JC, Mathavan K, Weir E, Larsen ISB, Halim A, Clausen H, Cousin H , Alfandari D , Hebert DN., Mol Biol Cell. February 1, 2020; 31 (3): 167-183.
Cut loose and run: The complex role of ADAM proteases during neural crest cell development. , Alfandari D , Taneyhill LA., Genesis. June 1, 2018; 56 (6-7): e23095.
Xenopus ADAM19 regulates Wnt signaling and neural crest specification by stabilizing ADAM13. , Li J, Perfetto M, Neuner R, Bahudhanapati H, Christian L, Mathavan K, Bridges LC, Alfandari D , Wei S ., Development. April 4, 2018; 145 (7):
Cranial Neural Crest Explants. , Cousin H , Alfandari D ., Cold Spring Harb Protoc. March 1, 2018; 2018 (3):
Editorial. , Artinger KB, Alfandari D , Taneyhill LA., Mech Dev. December 1, 2017; 148 1-2.
The ectodomain of cadherin-11 binds to erbB2 and stimulates Akt phosphorylation to promote cranial neural crest cell migration. , Mathavan K, Khedgikar V, Bartolo V, Alfandari D ., PLoS One. November 30, 2017; 12 (11): e0188963.
Dual control of pcdh8l/PCNS expression and function in Xenopus laevis neural crest cells by adam13/33 via the transcription factors tfap2α and arid3a. , Khedgikar V, Abbruzzese G , Mathavan K, Szydlo H, Cousin H , Alfandari D ., Elife. August 22, 2017; 6
Pa2G4 is a novel Six1 co-factor that is required for neural crest and otic development. , Neilson KM , Abbruzzesse G , Kenyon K , Bartolo V, Krohn P, Alfandari D , Moody SA ., Dev Biol. January 15, 2017; 421 (2): 171-182.
ADAM13 cleavage of cadherin-11 promotes CNC migration independently of the homophilic binding site. , Abbruzzese G , Becker SF, Kashef J , Alfandari D ., Dev Biol. July 15, 2016; 415 (2): 383-390.
Cadherin-11 localizes to focal adhesions and promotes cell-substrate adhesion. , Langhe RP, Gudzenko T, Bachmann M, Becker SF, Gonnermann C, Winter C, Abbruzzese G , Alfandari D , Kratzer MC, Franz CM, Kashef J ., Nat Commun. March 8, 2016; 7 10909.
Using Xenopus to discover new genes involved in branchiootorenal spectrum disorders. , Moody SA , Neilson KM , Kenyon KL , Alfandari D , Pignoni F., Comp Biochem Physiol C Toxicol Pharmacol. December 1, 2015; 178 16-24.
The Wnt receptor Frizzled-4 modulates ADAM13 metalloprotease activity. , Abbruzzese G , Gorny AK, Kaufmann LT, Cousin H , Kleino I, Steinbeisser H , Alfandari D ., J Cell Sci. March 15, 2015; 128 (6): 1139-49.
GSK3 and Polo-like kinase regulate ADAM13 function during cranial neural crest cell migration. , Abbruzzese G , Cousin H , Salicioni AM, Alfandari D ., Mol Biol Cell. December 15, 2014; 25 (25): 4072-82.
ADAM13 function is required in the 3 dimensional context of the embryo during cranial neural crest cell migration in Xenopus laevis. , Cousin H , Abbruzzese G , McCusker C, Alfandari D ., Dev Biol. August 15, 2012; 368 (2): 335-44.
[ADAM and cell migration: the unexpected role of the cytoplasmic domain]. , Cousin H , Alfandari D ., Med Sci (Paris). December 1, 2011; 27 (12): 1069-71.
Translocation of the cytoplasmic domain of ADAM13 to the nucleus is essential for Calpain8-a expression and cranial neural crest cell migration. , Cousin H , Abbruzzese G , Kerdavid E, Gaultier A , Alfandari D ., Dev Cell. February 15, 2011; 20 (2): 256-63.
Mechanism of Xenopus cranial neural crest cell migration. , Alfandari D , Cousin H , Marsden M ., Cell Adh Migr. January 1, 2010; 4 (4): 553-60.
Cadherin-11 regulates protrusive activity in Xenopus cranial neural crest cells upstream of Trio and the small GTPases. , Kashef J , Köhler A, Kuriyama S , Alfandari D , Mayor R , Wedlich D ., Genes Dev. June 15, 2009; 23 (12): 1393-8.
Xenopus ADAM19 is involved in neural, neural crest and muscle development. , Neuner R, Cousin H , McCusker C, Coyne M, Alfandari D ., Mech Dev. January 1, 2009; 126 (3-4): 240-55.
Extracellular cleavage of cadherin-11 by ADAM metalloproteases is essential for Xenopus cranial neural crest cell migration. , McCusker C, Cousin H , Neuner R, Alfandari D ., Mol Biol Cell. January 1, 2009; 20 (1): 78-89.
Life after proteolysis: Exploring the signaling capabilities of classical cadherin cleavage fragments. , McCusker CD, Alfandari D ., Commun Integr Biol. January 1, 2009; 2 (2): 155-7.
PACSIN2 regulates cell adhesion during gastrulation in Xenopus laevis. , Cousin H , Desimone DW , Alfandari D ., Dev Biol. July 1, 2008; 319 (1): 86-99.
Phosphorylation of IP3R1 and the regulation of [Ca2+]i responses at fertilization: a role for the MAP kinase pathway. , Lee B, Vermassen E, Yoon SY , Vanderheyden V, Ito J, Alfandari D , De Smedt H, Parys JB, Fissore RA., Development. November 1, 2006; 133 (21): 4355-65.
The Xenopus embryo as a model system for studies of cell migration. , DeSimone DW , Davidson L , Marsden M , Alfandari D ., Methods Mol Biol. January 1, 2005; 294 235-45.
A PTP-PEST-like protein affects alpha5beta1-integrin-dependent matrix assembly, cell adhesion, and migration in Xenopus gastrula. , Cousin H , Alfandari D ., Dev Biol. January 15, 2004; 265 (2): 416-32.
Integrin alpha5beta1 supports the migration of Xenopus cranial neural crest on fibronectin. , Alfandari D , Cousin H , Gaultier A , Hoffstrom BG, DeSimone DW ., Dev Biol. August 15, 2003; 260 (2): 449-64.
Cloning and expression patterns of dystroglycan during the early development of Xenopus laevis. , Moreau N, Alfandari D , Gaultier A , Cousin H , Darribère T ., Dev Genes Evol. July 1, 2003; 213 (7): 355-9.
The cysteine-rich domain regulates ADAM protease function in vivo. , Smith KM , Gaultier A , Cousin H , Alfandari D , White JM, DeSimone DW ., J Cell Biol. December 9, 2002; 159 (5): 893-902.
ADAM13 disintegrin and cysteine-rich domains bind to the second heparin-binding domain of fibronectin. , Gaultier A , Cousin H , Darribère T , Alfandari D ., J Biol Chem. June 28, 2002; 277 (26): 23336-44.
Xenopus ADAM 13 is a metalloprotease required for cranial neural crest-cell migration. , Alfandari D , Cousin H , Gaultier A , Smith K, White JM, Darribère T , DeSimone DW ., Curr Biol. June 26, 2001; 11 (12): 918-30.
PACSIN2 is a regulator of the metalloprotease/ disintegrin ADAM13. , Cousin H , Gaultier A , Bleux C, Darribère T , Alfandari D ., Dev Biol. November 1, 2000; 227 (1): 197-210.
Neural crest-specific and general expression of distinct metalloprotease-disintegrins in early Xenopus laevis development. , Cai H, Krätzschmar J, Alfandari D , Hunnicutt G, Blobel CP ., Dev Biol. December 15, 1998; 204 (2): 508-24.
ADAM 13: a novel ADAM expressed in somitic mesoderm and neural crest cells during Xenopus laevis development. , Alfandari D , Wolfsberg TG, White JM, DeSimone DW ., Dev Biol. February 15, 1997; 182 (2): 314-30.
Integrin alpha v subunit is expressed on mesodermal cell surfaces during amphibian gastrulation. , Alfandari D , Whittaker CA, DeSimone DW , Darribère T ., Dev Biol. August 1, 1995; 170 (2): 249-61.
Purification and partial characterization of Xenopus laevis tenascin from the XTC cell line. , Riou JF , Alfandari D , Eppe M, Tacchetti C, Chiquet M, Boucaut JC , Thiery JP, Levi G., FEBS Lett. February 25, 1991; 279 (2): 346-50.