Michael Perry - Publications

Publications (28)

XB-PERS-647

Publications By Michael Perry

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The S1 helix critically regulates the finely tuned gating of Kv11.1 channels., Phan K, Ng CA, David E, Shishmarev D, Kuchel PW, Vandenberg JI, Perry MD., J Biol Chem. May 5, 2017; 292 (18): 7688-7705.
Tyrosine Residues from the S4-S5 Linker of Kv11.1 Channels Are Critical for Slow Deactivation., Ng CA, Gravel AE, Perry MD, Arnold AA, Marcotte I, Vandenberg JI., J Biol Chem. August 12, 2016; 291 (33): 17293-302.
Rescue of protein expression defects may not be enough to abolish the pro-arrhythmic phenotype of long QT type 2 mutations., Perry MD, Ng CA, Phan K, David E, Steer K, Hunter MJ, Mann SA, Imtiaz M, Hill AP, Ke Y, Vandenberg JI., J Physiol. July 15, 2016; 594 (14): 4031-49.
Multiple interactions between cytoplasmic domains regulate slow deactivation of Kv11.1 channels., Ng CA, Phan K, Hill AP, Vandenberg JI, Perry MD., J Biol Chem. September 12, 2014; 289 (37): 25822-32.
C-terminal β9-strand of the cyclic nucleotide-binding homology domain stabilizes activated states of Kv11.1 channels., Ng CA, Ke Y, Perry MD, Tan PS, Hill AP, Vandenberg JI., PLoS One. October 4, 2013; 8 (10): e77032.
Hydrophobic interactions between the voltage sensor and pore mediate inactivation in Kv11.1 channels., Perry MD, Wong S, Ng CA, Vandenberg JI., J Gen Physiol. September 1, 2013; 142 (3): 275-88.
Pore helices play a dynamic role as integrators of domain motion during Kv11.1 channel inactivation gating., Perry MD, Ng CA, Vandenberg JI., J Biol Chem. April 19, 2013; 288 (16): 11482-91.
Voltage-sensing domain mode shift is coupled to the activation gate by the N-terminal tail of hERG channels., Tan PS, Perry MD, Ng CA, Vandenberg JI, Hill AP., J Gen Physiol. September 1, 2012; 140 (3): 293-306.
PD-118057 contacts the pore helix of hERG1 channels to attenuate inactivation and enhance K+ conductance., Perry M, Sachse FB, Abbruzzese J, Sanguinetti MC., Proc Natl Acad Sci U S A. November 24, 2009; 106 (47): 20075-80.
A single amino acid difference between ether-a-go-go- related gene channel subtypes determines differential sensitivity to a small molecule activator., Perry M, Sanguinetti MC., Mol Pharmacol. April 1, 2008; 73 (4): 1044-51.
Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator., Perry M, Sachse FB, Sanguinetti MC., Proc Natl Acad Sci U S A. August 21, 2007; 104 (34): 13827-32.
Drug binding interactions in the inner cavity of HERG channels: molecular insights from structure-activity relationships of clofilium and ibutilide analogs., Perry M, Stansfeld PJ, Leaney J, Wood C, de Groot MJ, Leishman D, Sutcliffe MJ, Mitcheson JS., Mol Pharmacol. February 1, 2006; 69 (2): 509-19.
The low-potency, voltage-dependent HERG blocker propafenone--molecular determinants and drug trapping., Witchel HJ, Dempsey CE, Sessions RB, Perry M, Milnes JT, Hancox JC, Mitcheson JS., Mol Pharmacol. November 1, 2004; 66 (5): 1201-12.
Structural determinants of HERG channel block by clofilium and ibutilide., Perry M, de Groot MJ, Helliwell R, Leishman D, Tristani-Firouzi M, Sanguinetti MC, Mitcheson J., Mol Pharmacol. August 1, 2004; 66 (2): 240-9.
Autoactivation of Xenopus MyoD transcription and its inhibition by USF., Lun Y, Sawadogo M, Perry M., Cell Growth Differ. March 1, 1997; 8 (3): 275-82.
Interaction of the CCAAT displacement protein with shared regulatory elements required for transcription of paired histone genes., el-Hodiri HM, Perry M., Mol Cell Biol. July 1, 1995; 15 (7): 3587-96.
Activation of Xenopus MyoD transcription by members of the MEF2 protein family., Wong MW, Pisegna M, Lu MF, Leibham D, Perry M., Dev Biol. December 1, 1994; 166 (2): 683-95.
Binding of TFIID and MEF2 to the TATA element activates transcription of the Xenopus MyoDa promoter., Leibham D, Wong MW, Cheng TC, Schroeder S, Weil PA, Olson EN, Perry M., Mol Cell Biol. January 1, 1994; 14 (1): 686-99.
Histone H2B gene transcription during Xenopus early development requires functional cooperation between proteins bound to the CCAAT and octamer motifs., Hinkley C, Perry M., Mol Cell Biol. October 1, 1992; 12 (10): 4400-11.
Sequential expression of multiple POU proteins during amphibian early development., Hinkley CS, Martin JF, Leibham D, Perry M., Mol Cell Biol. February 1, 1992; 12 (2): 638-49.
Differential expression of two distinct MyoD genes in Xenopus., Scales JB, Olson EN, Perry M., Cell Growth Differ. December 1, 1991; 2 (12): 619-29.
A variant octamer motif in a Xenopus H2B histone gene promoter is not required for transcription in frog oocytes., Hinkley C, Perry M., Mol Cell Biol. February 1, 1991; 11 (2): 641-54.
Two distinct Xenopus genes with homology to MyoD1 are expressed before somite formation in early embryogenesis., Scales JB, Olson EN, Perry M., Mol Cell Biol. April 1, 1990; 10 (4): 1516-24.
Measurement of histone mRNA transcript abundance in Xenopus oocytes by a quantitative primer extension assay., Brashears-Macatee S, Hinkley C, Perry M., Mol Reprod Dev. January 1, 1990; 25 (1): 22-7.
Promoter sequences required for transcription of Xenopus laevis histone genes in injected frog oocyte nuclei., Heindl LM, Weil TS, Perry M., Mol Cell Biol. September 1, 1988; 8 (9): 3676-82.
Major transitions in histone gene expression do not occur during development in Xenopus laevis., Perry M, Thomsen GH, Roeder RG., Dev Biol. August 1, 1986; 116 (2): 532-8.
Genomic organization and nucleotide sequence of two distinct histone gene clusters from Xenopus laevis. Identification of novel conserved upstream sequence elements., Perry M, Thomsen GH, Roeder RG., J Mol Biol. October 5, 1985; 185 (3): 479-99.
Microfilaments in the external surface layer of the early amphibian embryo., Perry MM., J Embryol Exp Morphol. February 1, 1975; 33 (1): 127-46.

The S1 helix critically regulates the finely tuned gating of Kv11.1 channels., Phan K, Ng CA, David E, Shishmarev D, Kuchel PW, Vandenberg JI, Perry MD., J Biol Chem. May 5, 2017; 292 (18): 7688-7705.

Tyrosine Residues from the S4-S5 Linker of Kv11.1 Channels Are Critical for Slow Deactivation., Ng CA, Gravel AE, Perry MD, Arnold AA, Marcotte I, Vandenberg JI., J Biol Chem. August 12, 2016; 291 (33): 17293-302.

Rescue of protein expression defects may not be enough to abolish the pro-arrhythmic phenotype of long QT type 2 mutations., Perry MD, Ng CA, Phan K, David E, Steer K, Hunter MJ, Mann SA, Imtiaz M, Hill AP, Ke Y, Vandenberg JI., J Physiol. July 15, 2016; 594 (14): 4031-49.

Multiple interactions between cytoplasmic domains regulate slow deactivation of Kv11.1 channels., Ng CA, Phan K, Hill AP, Vandenberg JI, Perry MD., J Biol Chem. September 12, 2014; 289 (37): 25822-32.

C-terminal β9-strand of the cyclic nucleotide-binding homology domain stabilizes activated states of Kv11.1 channels., Ng CA, Ke Y, Perry MD, Tan PS, Hill AP, Vandenberg JI., PLoS One. October 4, 2013; 8 (10): e77032.

Hydrophobic interactions between the voltage sensor and pore mediate inactivation in Kv11.1 channels., Perry MD, Wong S, Ng CA, Vandenberg JI., J Gen Physiol. September 1, 2013; 142 (3): 275-88.

Pore helices play a dynamic role as integrators of domain motion during Kv11.1 channel inactivation gating., Perry MD, Ng CA, Vandenberg JI., J Biol Chem. April 19, 2013; 288 (16): 11482-91.

Voltage-sensing domain mode shift is coupled to the activation gate by the N-terminal tail of hERG channels., Tan PS, Perry MD, Ng CA, Vandenberg JI, Hill AP., J Gen Physiol. September 1, 2012; 140 (3): 293-306.

PD-118057 contacts the pore helix of hERG1 channels to attenuate inactivation and enhance K+ conductance., Perry M, Sachse FB, Abbruzzese J, Sanguinetti MC., Proc Natl Acad Sci U S A. November 24, 2009; 106 (47): 20075-80.

A single amino acid difference between ether-a-go-go- related gene channel subtypes determines differential sensitivity to a small molecule activator., Perry M, Sanguinetti MC., Mol Pharmacol. April 1, 2008; 73 (4): 1044-51.

Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator., Perry M, Sachse FB, Sanguinetti MC., Proc Natl Acad Sci U S A. August 21, 2007; 104 (34): 13827-32.

Drug binding interactions in the inner cavity of HERG channels: molecular insights from structure-activity relationships of clofilium and ibutilide analogs., Perry M, Stansfeld PJ, Leaney J, Wood C, de Groot MJ, Leishman D, Sutcliffe MJ, Mitcheson JS., Mol Pharmacol. February 1, 2006; 69 (2): 509-19.

The low-potency, voltage-dependent HERG blocker propafenone--molecular determinants and drug trapping., Witchel HJ, Dempsey CE, Sessions RB, Perry M, Milnes JT, Hancox JC, Mitcheson JS., Mol Pharmacol. November 1, 2004; 66 (5): 1201-12.

Structural determinants of HERG channel block by clofilium and ibutilide., Perry M, de Groot MJ, Helliwell R, Leishman D, Tristani-Firouzi M, Sanguinetti MC, Mitcheson J., Mol Pharmacol. August 1, 2004; 66 (2): 240-9.

Autoactivation of Xenopus MyoD transcription and its inhibition by USF., Lun Y, Sawadogo M, Perry M., Cell Growth Differ. March 1, 1997; 8 (3): 275-82.

Interaction of the CCAAT displacement protein with shared regulatory elements required for transcription of paired histone genes., el-Hodiri HM, Perry M., Mol Cell Biol. July 1, 1995; 15 (7): 3587-96.

Activation of Xenopus MyoD transcription by members of the MEF2 protein family., Wong MW, Pisegna M, Lu MF, Leibham D, Perry M., Dev Biol. December 1, 1994; 166 (2): 683-95.

Binding of TFIID and MEF2 to the TATA element activates transcription of the Xenopus MyoDa promoter., Leibham D, Wong MW, Cheng TC, Schroeder S, Weil PA, Olson EN, Perry M., Mol Cell Biol. January 1, 1994; 14 (1): 686-99.

Histone H2B gene transcription during Xenopus early development requires functional cooperation between proteins bound to the CCAAT and octamer motifs., Hinkley C, Perry M., Mol Cell Biol. October 1, 1992; 12 (10): 4400-11.

Sequential expression of multiple POU proteins during amphibian early development., Hinkley CS, Martin JF, Leibham D, Perry M., Mol Cell Biol. February 1, 1992; 12 (2): 638-49.

Differential expression of two distinct MyoD genes in Xenopus., Scales JB, Olson EN, Perry M., Cell Growth Differ. December 1, 1991; 2 (12): 619-29.

A variant octamer motif in a Xenopus H2B histone gene promoter is not required for transcription in frog oocytes., Hinkley C, Perry M., Mol Cell Biol. February 1, 1991; 11 (2): 641-54.

Two distinct Xenopus genes with homology to MyoD1 are expressed before somite formation in early embryogenesis., Scales JB, Olson EN, Perry M., Mol Cell Biol. April 1, 1990; 10 (4): 1516-24.

Measurement of histone mRNA transcript abundance in Xenopus oocytes by a quantitative primer extension assay., Brashears-Macatee S, Hinkley C, Perry M., Mol Reprod Dev. January 1, 1990; 25 (1): 22-7.

Promoter sequences required for transcription of Xenopus laevis histone genes in injected frog oocyte nuclei., Heindl LM, Weil TS, Perry M., Mol Cell Biol. September 1, 1988; 8 (9): 3676-82.

Major transitions in histone gene expression do not occur during development in Xenopus laevis., Perry M, Thomsen GH, Roeder RG., Dev Biol. August 1, 1986; 116 (2): 532-8.

Genomic organization and nucleotide sequence of two distinct histone gene clusters from Xenopus laevis. Identification of novel conserved upstream sequence elements., Perry M, Thomsen GH, Roeder RG., J Mol Biol. October 5, 1985; 185 (3): 479-99.

Microfilaments in the external surface layer of the early amphibian embryo., Perry MM., J Embryol Exp Morphol. February 1, 1975; 33 (1): 127-46.

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