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Profile Publications (22)
XB-PERS-690

Publications By Karen Symes

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PDGF-A interactions with fibronectin reveal a critical role for heparan sulfate in directed cell migration during Xenopus gastrulation., Smith EM, Mitsi M, Nugent MA, Symes K., Proc Natl Acad Sci U S A. December 22, 2009; 106 (51): 21683-8.   


Threonine 393 of beta-catenin regulates interaction with Axin., Wu H, Symes K, Seldin DC, Dominguez I., J Cell Biochem. September 1, 2009; 108 (1): 52-63.


Apoptosis regulates notochord development in Xenopus., Malikova MA, Van Stry M, Symes K., Dev Biol. November 15, 2007; 311 (2): 434-48.   


Migrating anterior mesoderm cells and intercalating trunk mesoderm cells have distinct responses to Rho and Rac during Xenopus gastrulation., Ren R, Nagel M, Tahinci E, Winklbauer R, Symes K., Dev Dyn. April 1, 2006; 235 (4): 1090-9.


Distinct effectors of platelet-derived growth factor receptor-alpha signaling are required for cell survival during embryogenesis., Van Stry M, Kazlauskas A, Schreiber SL, Symes K., Proc Natl Acad Sci U S A. June 7, 2005; 102 (23): 8233-8.   


A role for CK2alpha/beta in Xenopus early embryonic development., Dominguez I, Mizuno J, Wu H, Imbrie GA, Symes K, Seldin DC., Mol Cell Biochem. June 1, 2005; 274 (1-2): 125-31.


Protein kinase CK2 is required for dorsal axis formation in Xenopus embryos., Dominguez I, Mizuno J, Wu H, Song DH, Symes K, Seldin DC., Dev Biol. October 1, 2004; 274 (1): 110-24.


Guidance of mesoderm cell migration in the Xenopus gastrula requires PDGF signaling., Nagel M, Tahinci E, Symes K, Winklbauer R., Development. June 1, 2004; 131 (11): 2727-36.   


The mitochondrial-apoptotic pathway is triggered in Xenopus mesoderm cells deprived of PDGF receptor signaling during gastrulation., Van Stry M, McLaughlin KA, Ataliotis P, Symes K., Dev Biol. April 1, 2004; 268 (1): 232-42.   


Distinct functions of Rho and Rac are required for convergent extension during Xenopus gastrulation., Tahinci E, Symes K., Dev Biol. July 15, 2003; 259 (2): 318-35.   


Small-molecule control of insulin and PDGF receptor signaling and the role of membrane attachment., Yang J, Symes K, Mercola M, Schreiber SL., Curr Biol. January 1, 1998; 8 (1): 11-8.


Embryonic mesoderm cells spread in response to platelet-derived growth factor and signaling by phosphatidylinositol 3-kinase., Symes K, Mercola M., Proc Natl Acad Sci U S A. September 3, 1996; 93 (18): 9641-4.


PDGF signalling is required for gastrulation of Xenopus laevis., Ataliotis P, Symes K, Chou MM, Ho L, Mercola M., Development. September 1, 1995; 121 (9): 3099-110.   


Localization of PDGF A and PDGFR alpha mRNA in Xenopus embryos suggests signalling from neural ectoderm and pharyngeal endoderm to neural crest cells., Ho L, Symes K, Yordán C, Gudas LJ, Mercola M., Mech Dev. December 1, 1994; 48 (3): 165-74.


Morphological differences in Xenopus embryonic mesodermal cells are specified as an early response to distinct threshold concentrations of activin., Symes K, Yordán C, Mercola M., Development. August 1, 1994; 120 (8): 2339-46.


Mesoderm induction and the control of gastrulation in Xenopus laevis: the roles of fibronectin and integrins., Smith JC, Symes K, Hynes RO, DeSimone D., Development. February 1, 1990; 108 (2): 229-38.


The biological effects of XTC-MIF: quantitative comparison with Xenopus bFGF., Green JB, Howes G, Symes K, Cooke J, Smith JC., Development. January 1, 1990; 108 (1): 173-83.


Potentiation by the lithium ion of morphogenetic responses to a Xenopus inducing factor., Cooke J, Symes K, Smith EJ., Development. March 1, 1989; 105 (3): 549-58.


Inducing factors and the control of mesodermal pattern in Xenopus laevis., Smith JC, Cooke J, Green JB, Howes G, Symes K., Development. January 1, 1989; 107 Suppl 149-59.


Mesoderm induction in Xenopus laevis: responding cells must be in contact for mesoderm formation but suppression of epidermal differentiation can occur in single cells., Symes K, Yaqoob M, Smith JC., Development. December 1, 1988; 104 (4): 609-18.


Purification, partial characterization and biological effects of the XTC mesoderm-inducing factor., Smith JC, Yaqoob M, Symes K., Development. July 1, 1988; 103 (3): 591-600.


The Xenopus animal pole blastomere., Smith JC, Symes K, Heasman J, Snape A, Wylie CC., Bioessays. November 1, 1987; 7 (5): 229-34.

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