18th International Xenopus Conference
The 18th International Xenopus Conference was held virtually August 15-19, 2021.
Content for registrants will be available until Friday, September 17, 2021.
Registrants click here to log in.
Official conference website.
Many thanks to the organizers, speakers, presenters, and participants!
Congratulations to Helen Willsey and Alice Godden named John Gurdon outstanding speaker award winners!
Conference Programme
Sunday, 15 August 2021
Session 1 - Chair: Christof Niehrs
PL01 - Aaron Zorn
The CLEAR consortium: discovering the developmental basis of trachea-esophageal birth defects
O01 - Clayton Gordy
One-Eared Frogs: Insights into Brainstem Sensorimotor Plasticity
O02 - Jennifer Landino
Changes in neighbor cell contractility alter the speed and success of epithelial cytokinesis
S01 - Jin-Kwan Han
Ripply2.2 induces VegT degradation in head organizer
S02 - Laurent Kodjabachian
Centriole synthesis in multiciliated cells
O03 - Seongmin Yun
Development of deep-learning-based high-throughput phenotype screening platform of Xenopus laevis embryos
O04 - Gerhard Schlosser
The role of Eya1 for otic neurogenesis in Xenopus laevis
Session 2 - Chair: Gerhard Schlosser
S03 - Roberto Mayor
Interplay between chemical and mechanical cues during neural crest migration
S04 - Stefan Hoppler
Wnt target genes in Xenopus development
S05 - Vaibhav Pai
Biophysical Control of Organogenesis: How Membrane Voltage Patterns Regulate Embryonic Neural Patterning and Regeneration
S06 - Robert Huebener
Mechanical heterogeneity along single cell-cell junctions is driven by lateral clustering of cadherins during vertebrate axis elongation
Session 3 - Chair: John Wallingford
S07 - Jerome Julien
Editing the sperm epigenome
S08 - Soeren Lienkamp
Models of kidney disease and ciliopathies
S09 - Rachel Miller
The Wnt/PCP formin, Daam1, drives cell-cell adhesion during nephron development
S10 - Lance Davidson
Mechanical discordance and jamming during neurulation. Or, What can we learn just by watching?
Sit down & chat - “All Sorts of People make Great Scientists; how do they do it?”
Monday, 16 August 2021
Live poster sessions + networking
Xenbase workshop 1 - GEO data
Explore RNA/ChIP-Seq data from GEO and Differentially Expressed Genes (DEG) on Xenbase
Session 1 - Chair: Steffan Hoppler
PL02: IXB - Young PI Andrea Wills
Decoding the metabolic requirements for regeneration
O05 - Hyo Jung Sim
Study on the functions of ERAD pathway in cartilage formation and osteoarthritis
O06 - Eva Pillai
Mechanical control of chemical signalling in the developing Xenopus brain
S11 - Naota Ueno
Force-dependent remodeling of a tight junction protein ZO-1 is regulated by phase-separation
S12 - Eva Hormandser
O07 - Karel Dorey
Identification of the molecular switch regulating the transition from proliferation to differentiation during spinal cord regeneration
O08 - Marcus Maerker
Bicc1 regulates left-right patterning through post-transcriptional control of the Nodal-inhibitor Dand5
Session 2 - Chair: Muriel Perron
S13 - Anne-H Monsoro-Burq
Spatio-temporal coordination of BMP and Wnt signaling by the scaffolding protein FHL3, a novel enhancer of BMP signaling, controls several steps of neural crest early development
S14 - Matt Good
Cell Size and Cell Cycle Dependent Mechanisms of Zygotic Genome Activation
S15- Carole LaBonne
S16- Coral Zhou
Mechanisms of mitotic chromosome scaling in Xenopus laevis
Session 3 - Chair: Marko Horb
S17 - Hazel Sive
The Extreme Anterior Domain: a Target for Microcephaly
S18 - Philipp Vick
Regulation of FGF signaling by the endosomal compartment - deep and superficial insights from the mesoderm
S19 - Orson Moritz
Modeling CRISPR-based gene therapies for retinitis pigmentosa in X. laevis
S20 - Leonid Peshkin
Xenopus proteomics Atlas
Poster session
Sit down & chat - career transitions
Xenbase workshop 1 - GEO data Repeat
Explore RNA/ChIP-Seq data from GEO and Differentially Expressed Genes (DEG) on Xenbase
Tuesday, 17 August 2021
Live poster sessions + networking
Xenbase Workshop 2 - Phenotypes
Explore Xenopus phenotypes effecting anatomy, biological processes, changes in gene expression and models of human disease
Session 1 - Chair: Roberto Mayor
PL03 - Jim Smith
From frogs to humans—just as we’d hoped
O09 - Ken Cho
Patterning the chromatin state along the germ layer axis in Xenopus
O10 - Marjolein Carron
Functional characterization of a Xenopus tropicalis knockout and a human cellular model of RCBTB1-associated inherited retinal disease shows involvement of RCBTB1 in the cellular response to oxidative stress
S21 - Makoto Nakamura
The AP-1 transcription factor JunB and TGF-β1 ligand are critical components of the early injury response leading to cell proliferation in Xenopus tadpole tail regeneration
S22 - Jenny Gallop
Intervening in membrane-triggered actin assembly
O11- Alexia Tasca
Multiciliated cells can undergo direct fate conversion through Notch signaling
O12 - Aparna Baxi
Time-resolved proteomic analysis of inner ear development in Xenopus laevis
Session 2 - Chair: Anne Monsoro-Burq
S23- Bill Bement
Further adventures in cortical excitability
S24 - Laura-Ann Lowery
Investigating the role of the CoREST repressor complex in melanoma metastasis in vivo
S25 - Lora Sweeney
Defining tetrapod motor circuit diversity across frog metamorphosis and vertebrate evolution
S26 - Enrique Amaya
Metabolic reprogramming during early embryonic development and appendage regeneration
Session 3 - Chair: Robert Grainger
S27 - Frank Conlon
The Evolution of the X-Chromosome and Cardiac Sex Disparities
S28 - Peter Walentek
Using Xenopus to understand mucociliary epithelial development, remodeling and diseases
S29 - Sally Moody
Human SIX1 mutations cause gene expression and morphological changes in craniofacial structures
S30 - Rudi Winklbauer
Cell adhesion in the Xenopus gastrula
Poster session
Sit down & chat - Xenopus Heath & Care
Xenbase Workshop 2 - Phenotypes repeat
Explore Xenopus phenotypes effecting anatomy, biological processes, changes in gene expression and models of human disease
Wednesday, 18 August 2021
Live poster sessions
13.00 - 16.00 Session 1: Chair: Gert Veenstra
PL04 - Karen Liu
Pathological missense variants in CTNND1 predict tissue specific protein functions
O13 - Thomas Naert
XenoVision: Deep learning for embryonic disease modeling
O14 - Alice Godden
Investigating the role of microRNAs in the development of Xenopus neual crest with CRISPR-Cas9
S31 - Yuuri Yasuoka
Comparing fluctuation of gene expression profiles in embryos to dissect diversification of Xenopus tropicalis strains
S32 - Gert Veenstra
From histone modifications to gene regulation
O15 - Podrowsky
Cell proliferation in Xenopus embryos antagonizes the accumulation of repressive histone marks by replicational dilution
O16 - Banerjee
A Xenopus laevis epilepsy model to test alternative therapy for Intractable Epilepsy
16.20 - 18.10 Session 2 - Chair: Sally Moody
S33 - Christof Niehrs
Novel mechanisms of R-spondins during early Xenopus development
S34 - Helen Willsey
Using frogs to identify convergent biology underlying complex genetic disorders including autism
S35 - Kristian Franze
The chemomechanical guidance of neuronal axons in the developing Xenopus brain
S36 - Mustafa Khokha
The nuclear transport of beta-catenin
Session 3 - Chair: Amy Sater
S37 - Muriel Perron
Xenopus retina regeneration: linking inflammation and stem cell reactivation
S38 - Peter Nemes
In vivo Subcellular Mass Spectrometry for Functional Cell/Developmental Biology
S39 - Richard Harland
Chromosome evolution in frogs
S40 - John Gurdon
A long transcription factor dwell time stabilizes cell differentiation
Poster Session
Thursday, 19 August 2021
Chair: Hazel Sive
PL05 - Marc Kirschner
S41 - Hajime Ogino
Morphological and behavioral characteristics of Xenopus tropicalis inbred strains in NBRP
S42 - Dom Alfandari
Production and Characterization of Monoclonal antibodies to Xenopus proteins
S43 - Esther Pearl
The Experimental Design Assistant: helping you design more rigorous in vivo experiments
S44 - Marko Horb
Xenopus Mutant Resource
S45 - Jacques Robert
Xenopus laevis Research Resource for Immunobiology (XLRRI): update and preparation for competing renewal in 2022
S46 - Matthew Guille
The EXRC: successful changes and unexpected challenges
Closing session & prize giving
Last Updated: 2021-09-10