| Monarch Ortholog Phenotypes
|
Human (43 sources):
Abnormal dental enamel morphology,
Abnormal form of the vertebral bodies,
Abnormality of the voice,
Abnormally high-pitched voice,
Abnormal metaphysis morphology,
Abnormal rib morphology,
Blue sclerae,
Bowing of the long bones,
Communicating hydrocephalus,
Coronal craniosynostosis,
Crumpled long bones,
Delayed eruption of teeth,
Dentinogenesis imperfecta,
Downslanted palpebral fissures,
Failure to thrive,
Frontal bossing,
Global developmental delay,
High palate,
Hydrocephalus,
Hypertelorism,
Hypotonia,
Intrauterine growth retardation,
Kyphosis,
Lambdoidal craniosynostosis,
Macrocephaly,
Micrognathia,
Microretrognathia,
Midface retrusion,
Narrow iliac wing,
obsolete Joint hyperflexibility,
Oligohydramnios,
Osteopenia,
Pectus excavatum,
Platyspondyly,
Proptosis,
Recurrent fractures,
Scoliosis,
Short stature,
Skeletal dysplasia,
Thin ribs,
Triangular face,
Turricephaly,
Wormian bones
[+]
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Mouse (4 sources):
embryonic lethality before implantation, complete penetrance,
embryonic lethality during organogenesis, complete penetrance,
no abnormal phenotype detected,
preweaning lethality, complete penetrance
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.