gclm Phenotypes

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Phenotypes

XB-GENEPAGE-1014944

Gene Symbol: gclm Gene Name: glutamate-cysteine ligase, modifier subunit

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (9 sources): abnormal cingulate gyrus morphology, decreased circulating cysteine level, decreased cysteine level, increased cellular sensitivity to hydrogen peroxide, increased circulating alanine transaminase level, increased physiological sensitivity to xenobiotic, increased sensitivity to xenobiotic induced morbidity/mortality, increased susceptibility to neuronal excitotoxicity, oxidative stress

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (9 sources): abnormal cingulate gyrus morphology, decreased circulating cysteine level, decreased cysteine level, increased cellular sensitivity to hydrogen peroxide, increased circulating alanine transaminase level, increased physiological sensitivity to xenobiotic, increased sensitivity to xenobiotic induced morbidity/mortality, increased susceptibility to neuronal excitotoxicity, oxidative stress