tnik Phenotypes

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Phenotypes

Gene Literature (3)

Nucleotides (280)

Interactants (209)

XB-GENEPAGE-480066

Gene Symbol: tnik Gene Name: TRAF2 and NCK interacting kinase

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: tnik assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (39 sources): Abnormal facial shape, Absent septum pellucidum, Autistic behavior, Cerebral atrophy, Cerebral visual impairment, Chorea, Cortical dysplasia, Delayed speech and language development, Depression, Dyskinesia, Dystonia, EEG with focal epileptiform discharges, EEG with generalized epileptiform discharges, Epileptic spasm, Focal-onset seizure, Generalized hypotonia, Generalized-onset seizure, Global developmental delay, Hyperactivity, Hypoplasia of the corpus callosum, Hypotonia, Hypsarrhythmia, Impulsivity, Intellectual disability, Intellectual disability, mild, Intellectual disability, moderate, Intellectual disability, severe, Large basal ganglia, Microcephaly, Motor delay, Motor stereotypy, Multifocal epileptiform discharges, Nasogastric tube feeding, Polymicrogyria, Poor speech, Seizure, Short attention span, Sleep abnormality, Spasticity [+]
Mouse (19 sources): abnormal adipose tissue amount, abnormal bone mineralization, abnormal discrimination learning, abnormal excitatory postsynaptic potential, abnormal lean body mass, abnormal miniature excitatory postsynaptic currents, abnormal neuron differentiation, abnormal object recognition memory, decreased bone mineral content, decreased cerebellar granule cell number, decreased circulating glucose level, decreased incidence of tumors by chemical induction, decreased lean body mass, enhanced paired-pulse facilitation, immune system phenotype, increased bone mineral content, increased lean body mass, nervous system phenotype, no abnormal phenotype detected [+]
View all ortholog results at Monarch