nfe2l1 Phenotypes

Phenotypes

XB-GENEPAGE-481362

Gene Symbol: nfe2l1 Gene Name: NFE2 like bZIP transcription factor 1

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (26 sources): abnormal blood homeostasis, abnormal erythropoiesis, abnormal hematopoietic system morphology/development, abnormal pancreatic beta cell morphology, absent mesoderm, decreased circulating glucose level, decreased embryo size, decreased hematocrit, embryonic growth retardation, embryonic lethality between implantation and somite formation, incomplete penetrance, embryonic lethality during organogenesis, complete penetrance, failure of primitive streak formation, growth/size/body region phenotype, homeostasis/metabolism phenotype, increased circulating alanine transaminase level, increased circulating aspartate transaminase level, increased hepatocellular carcinoma incidence, increased liver adenoma incidence, increased liver weight, increased nucleated erythrocyte cell number, increased susceptibility to diet-induced non-insulin dependent diabetes, lethality throughout fetal growth and development, incomplete penetrance, neonatal lethality, complete penetrance, oxidative stress, pale liver, small liver [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (26 sources): abnormal blood homeostasis, abnormal erythropoiesis, abnormal hematopoietic system morphology/development, abnormal pancreatic beta cell morphology, absent mesoderm, decreased circulating glucose level, decreased embryo size, decreased hematocrit, embryonic growth retardation, embryonic lethality between implantation and somite formation, incomplete penetrance, [+]