gsk3b Phenotypes

Summary

Expression

Phenotypes

Gene Literature (174)

XB-GENEPAGE-487097

Gene Symbol: gsk3b Gene Name: glycogen synthase kinase 3 beta

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: gsk3b manipulated (10 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + gsk3b (9 sources), Xla Wt + gsk3b + endoderm explant (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (42 sources): abnormal bone healing, abnormal contextual conditioning behavior, abnormal glycogen homeostasis, abnormal hepatocyte morphology, abnormal learning/memory/conditioning, abnormal osteoblast physiology, abnormal palatal shelf elevation, abnormal palate development, abnormal proximal convoluted tubule morphology, abnormal renal tubule morphology, abnormal skeleton development, abnormal skeleton physiology, abnormal spatial reference memory, abnormal sternum ossification, abnormal Wallerian degeneration, behavioral despair, behavior/neurological phenotype, craniofacial phenotype, decreased circulating glucose level, decreased exploration in new environment, decreased myocardial infarct size, decreased prepulse inhibition, decreased P wave amplitude, delayed bone ossification, enhanced osteoblast differentiation, homeostasis/metabolism phenotype, increased bone mass, increased bone ossification, increased compact bone mass, increased compact bone thickness, increased compact bone volume, increased glycogen level, increased myocardial infarct size, increased trabecular bone mass, increased trabecular bone volume, lethality throughout fetal growth and development, complete penetrance, neonatal lethality, complete penetrance, no abnormal phenotype detected, palatal shelves fail to meet at midline, preweaning lethality, complete penetrance, renal/urinary system phenotype, xiphoid process foramen [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (42 sources): abnormal bone healing, abnormal contextual conditioning behavior, abnormal glycogen homeostasis, abnormal hepatocyte morphology, abnormal learning/memory/conditioning, abnormal osteoblast physiology, abnormal palatal shelf elevation, abnormal palate development, abnormal proximal convoluted tubule morphology, abnormal renal tubule morphology, [+]