tjp1 Phenotypes

Phenotypes

XB-GENEPAGE-490683

Gene Symbol: tjp1 Gene Name: tight junction protein 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: tjp1 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (33 sources): abnormal developmental vascular remodeling, abnormal embryonic tissue morphology, abnormal extraembryonic tissue morphology, abnormal glomerular filtration barrier morphology, abnormal kidney morphology, abnormal kidney pelvis morphology, abnormal notochord morphology, abnormal placental labyrinth vasculature morphology, abnormal podocyte foot process morphology, abnormal podocyte slit diaphragm morphology, abnormal visceral yolk sac morphology, abnormal vitelline vascular remodeling, abnormal vitelline vasculature morphology, absent podocyte slit diaphragm, decreased embryo size, detached podocyte, dilated allantois, dilated renal tubules, embryonic growth retardation, embryonic lethality during organogenesis, complete penetrance, failure of chorioallantoic fusion, failure of initiation of embryo turning, fused podocyte foot processes, granular kidney, increased allantois apoptosis, increased embryonic tissue cell apoptosis, increased neural tube apoptosis, increased renal glomerulus basement membrane thickness, kidney papillary atrophy, no abnormal phenotype detected, pale kidney, podocyte foot process effacement, renal cast [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (33 sources): abnormal developmental vascular remodeling, abnormal embryonic tissue morphology, abnormal extraembryonic tissue morphology, abnormal glomerular filtration barrier morphology, abnormal kidney morphology, abnormal kidney pelvis morphology, abnormal notochord morphology, abnormal placental labyrinth vasculature morphology, abnormal podocyte foot process morphology, abnormal podocyte slit diaphragm morphology, [+]