Broad thumb, Calcaneovalgus deformity, Camptodactyly, Camptodactyly of finger, Cataract, Clinodactyly, Coxa valga, Cryptorchidism, Cutis laxa, Deep philtrum, Deep-set nails, Delayed speech and language development, Depressed nasal bridge, Diastasis recti, Dimple chin, Downslanted palpebral fissures, Dysarthria, Dysharmonic skeletal maturation, Epicanthus, Feeding difficulties in infancy, Fine hair, Finger syndactyly, Flared femoral metaphysis, Flared humeral metaphysis, Flexion contracture, Gait disturbance, Generalized hypotonia, Global developmental delay, Hoarse voice, Hydrocele testis, Hypertelorism, Hypoplasia of penis, Hypoplastic iliac wing, Hypoplastic toenails, Hypotonia, Intellectual disability, Inverted nipples, Joint contracture of the hand, Joint stiffness, Kyphosis, Large hands, Lateral ventricle dilatation, Limited elbow extension, Limited knee extension, Long ear, Long foot, Long philtrum, Low-set ears, Macrocephaly, Macrotia, Mandibular prognathia, Melanocytic nevus, Metatarsus adductus, Micrognathia, Myopia, obsolete Joint hyperflexibility, obsolete Joint laxity, obsolete Low-set, posteriorly rotated ears, Osteopenia, Overlapping toe, Patent ductus arteriosus, Pes cavus, Poor coordination, Prominent fingertip pads, Ptosis, Radial deviation of finger, Redundant skin, Retrognathia, Round face, Sandal gap, Scoliosis, Seizure, Short fourth metatarsal, Short ribs, Slurred speech, Small nail, Sparse hair, Spasticity, Strabismus, Talipes equinovarus, Tall stature, Thin nail, Umbilical hernia, Wide nasal bridge