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XB-GENEPAGE-493421
fgd4 FYVE, RhoGEF and PH domain containing 4
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Computed annotations: fgd4 assayed (3 sources) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Human (15 sources): Areflexia, Decreased motor nerve conduction velocity, Decreased number of peripheral myelinated nerve fibers, Distal lower limb amyotrophy, Distal lower limb muscle weakness, Distal sensory impairment, Hyporeflexia, Motor delay, Onion bulb formation, Peripheral demyelination, [+] |
| Mouse (7 sources): abnormal action potential, abnormal lean body mass, abnormal myelin sheath morphology, decreased circulating alkaline phosphatase level, decreased grip strength, decreased lean body mass, nervous system phenotype |
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View all ortholog results at Monarch |