tgfbi Phenotypes

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Phenotypes

Gene Literature (24)

Nucleotides (167)

Interactants (294)

XB-GENEPAGE-5751246

Gene Symbol: tgfbi Gene Name: transforming growth factor beta induced

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
decreased size of the otic vesicle (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: tgfbi manipulated (1 source)
Computed annotations: tgfbi assayed (4 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + tgfbi MO (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (17 sources): Cataract, Corneal dystrophy, Corneal erosion, Corneal scarring, Granular corneal dystrophy, Juvenile epithelial corneal dystrophy, Lattice corneal dystrophy, Map-dot-fingerprint corneal dystrophy, Nodular corneal dystrophy, Opacification of the corneal stroma, Photophobia, Progressive visual loss, Punctate corneal dystrophy, Recurrent corneal erosions, Reduced visual acuity, Strabismus, Visual impairment [+]
Mouse (19 sources): abnormal cell nucleus morphology, abnormal chromosome morphology, abnormal corneal stroma morphology, abnormal pancreatic beta cell physiology, abnormal pancreatic islet morphology, abnormal retina inner nuclear layer thickness, decreased insulin secretion, decreased retina apoptosis, delayed wound healing, endocrine/exocrine gland phenotype, growth/size/body region phenotype, increased incidence of tumors by chemical induction, increased lymphoma incidence, increased malignant tumor incidence, increased pancreatic beta cell apoptosis, increased susceptibility to non-insulin-dependent diabetes, increased tumor incidence, premature death, vision/eye phenotype [+]
View all ortholog results at Monarch