Mouse (76 sources):
abnormal B-1a B cell morphology,
abnormal B-1 B cell morphology,
abnormal B cell activation,
abnormal B cell proliferation,
abnormal bone marrow cell number,
abnormal class switch recombination,
abnormal gut-associated lymphoid tissue morphology,
abnormal humoral immune response,
abnormal immature B cell morphology,
abnormal immunoglobulin heavy chain V(D)J recombination,
abnormal immunoglobulin light chain V-J recombination,
abnormal immunoglobulin V(D)J recombination,
abnormal kidney morphology,
abnormal late pro-B cell,
abnormal lymph node germinal center morphology,
abnormal marginal zone B cell morphology,
abnormal marginal zone B cell physiology,
abnormal mature B cell morphology,
abnormal Peyer's patch germinal center morphology,
abnormal somatic hypermutation frequency,
abnormal spleen B cell follicle morphology,
abnormal T cell differentiation,
abnormal thymus morphology,
absent B-1a cells,
absent B-1 B cells,
absent B-1b cells,
absent follicular B cells,
absent marginal zone B cells,
absent mature B cells,
absent Peyer's patches,
absent plasma cells,
absent pre-B cells,
absent spleen germinal center,
arrested B cell differentiation,
cellular phenotype,
decreased B-1a cell number,
decreased B-1b cell number,
decreased bone marrow cell number,
decreased double-negative T cell number,
decreased double-positive T cell number,
decreased follicular B cell number,
decreased IgG1 level,
decreased IgG2a level,
decreased IgG2b level,
decreased IgG3 level,
decreased immature B cell number,
decreased marginal zone B cell number,
decreased mature B cell number,
decreased pre-B cell number,
decreased transitional stage B cell number,
decreased transitional stage T2 B cell number,
enlarged lymph nodes,
enlarged thymus,
hematopoietic system phenotype,
immune system phenotype,
increased anti-nuclear antigen antibody level,
increased anti-single stranded DNA antibody level,
increased autoantibody level,
increased B cell apoptosis,
increased B cell proliferation,
increased chronic lymphocytic leukemia incidence,
increased early pro-B cell number,
increased IgG1 level,
increased IgG3 level,
increased late pro-B cell number,
increased lymphoma incidence,
increased marginal zone B cell number,
increased pre-B cell number,
increased pro-B cell number,
increased susceptibility to autoimmune diabetes,
increased T cell derived lymphoma incidence,
insulitis,
no abnormal phenotype detected,
premature death,
reduced male fertility,
small spleen
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