| Monarch Ortholog Phenotypes
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Human (3 sources):
Amelogenesis imperfecta,
Dental malocclusion,
obsolete Anterior open bite
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Mouse (19 sources):
abnormal coat appearance,
abnormal kidney morphology,
abnormal mammary gland morphology,
abnormal oral cavity morphology,
abnormal seminal vesicle morphology,
craniofacial phenotype,
decreased body size,
decreased grip strength,
decreased locomotor activity,
disheveled coat,
increased anxiety-related response,
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number,
increased neutrophil cell number,
periodontal pocket,
postnatal lethality, incomplete penetrance,
premature death,
shortened PQ interval,
small heart,
weakness
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.