| Monarch Ortholog Phenotypes
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Human (42 sources):
2-3 toe syndactyly,
Anxiety,
Attention deficit hyperactivity disorder,
Autistic behavior,
Babinski sign,
Bilateral tonic-clonic seizure,
Broad nasal tip,
Clinodactyly of the 2nd toe,
Delayed eruption of teeth,
Delayed speech and language development,
Depressed nasal bridge,
Downslanted palpebral fissures,
Drooling,
Facial palsy,
Generalized non-motor (absence) seizure,
Global developmental delay,
Hyperreflexia,
Intellectual disability,
Intellectual disability, moderate,
Intellectual disability, profound,
Intellectual disability, severe,
Language impairment,
Long palpebral fissure,
Long philtrum,
Macrocephaly,
Meckel diverticulum,
Microcephaly,
Midface retrusion,
Mild neurosensory hearing impairment,
Moderate sensorineural hearing impairment,
Obesity,
Periorbital fullness,
Pes planus,
Poor speech,
Pyloric stenosis,
Seizure,
Shortening of all distal phalanges of the fingers,
Small for gestational age,
Thick lower lip vermilion,
Thin upper lip vermilion,
Urinary incontinence,
Widened subarachnoid space
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Mouse (15 sources):
abnormal endometrium morphology,
abnormal female reproductive system morphology,
abnormal uterus physiology,
decreased body length,
decreased heart weight,
decreased lean body mass,
decreased litter size,
dilated uterus,
homeostasis/metabolism phenotype,
increased corpora lutea number,
[+]
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.