nrxn1 Phenotypes

Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Phenotypes

Gene Literature (3)

Nucleotides (283)

Interactants (83)

XB-GENEPAGE-952912

Gene Symbol: nrxn1 Gene Name: neurexin 1

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (63 sources): Abnormal cardiac ventricle morphology, Abnormal facial shape, Absent speech, Aggressive behavior, Autism, Brachycephaly, Broad-based gait, Bruxism, Cerebral cortical atrophy, Cerebral white matter hypoplasia, Chronic constipation, Cognitive impairment, Constipation, Cow milk allergy, Cryptorchidism, Depressed nasal bridge, Developmental regression, Dilation of Virchow-Robin spaces, Drooling, Dysphagia, Elevated circulating hepatic transaminase concentration, Epileptic encephalopathy, Failure to thrive, Feeding difficulties, Flat occiput, Frontal bossing, Gastroesophageal reflux, Generalized hypotonia, Gingival bleeding, Gluten intolerance, Hearing impairment, High anterior hairline, High-pitched cry, Hyperactivity, Hyperventilation, Hyporeflexia, Hypotonia, Hypsarrhythmia, Infantile muscular hypotonia, Infra-orbital crease, Intellectual disability, severe, Long philtrum, Mandibular prognathia, Motor stereotypy, obsolete Impaired social interactions, Plagiocephaly, Pointed chin, Poor speech, Precocious puberty, Prominent glabella, Protruding tongue, Pulmonic stenosis, Scoliosis, Seizure, Self-injurious behavior, Severe global developmental delay, Sleep-wake cycle disturbance, Strabismus, Telecanthus, Thin upper lip vermilion, Tricuspid regurgitation, Ventricular septal defect, Wide mouth [+]
Mouse (19 sources): abnormal circulating alkaline phosphatase level, abnormal excitatory postsynaptic currents, abnormal fasting circulating glucose level, abnormal grip strength, abnormal miniature excitatory postsynaptic currents, abnormal motor learning, abnormal nest building behavior, behavior/neurological phenotype, decreased circulating alkaline phosphatase level, decreased fasting circulating glucose level, decreased grip strength, decreased prepulse inhibition, decreased pulmonary respiratory rate, decreased synaptic glutamate release, enlarged stomach, increased grooming behavior, increased lean body mass, no abnormal phenotype detected, small thymus [+]
View all ortholog results at Monarch