| Monarch Ortholog Phenotypes
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Human (37 sources):
Abnormal cardiovascular system morphology,
Abnormal form of the vertebral bodies,
Abnormal intervertebral disk morphology,
Abnormality of immune system physiology,
Abnormality of the ureter,
Abnormal morphology of female internal genitalia,
Abnormal rib morphology,
Anomalous pulmonary venous return,
Anteverted nares,
Broad forehead,
Camptodactyly of finger,
Cleft palate,
Congenital diaphragmatic hernia,
Cryptorchidism,
Depressed nasal bridge,
Finger syndactyly,
Hypospadias,
Intellectual disability,
Intrauterine growth retardation,
Kyphosis,
Long philtrum,
Macrocephaly,
Meningocele,
Microcephaly,
obsolete Low-set, posteriorly rotated ears,
Prominent occiput,
Respiratory insufficiency,
Rib fusion,
Rib segmentation abnormalities,
Scoliosis,
Short neck,
Short stature,
Short thorax,
Spina bifida occulta,
Umbilical hernia,
Urogenital fistula,
Vertebral segmentation defect
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Mouse (12 sources):
abnormal myotome morphology,
abnormal rostral-caudal patterning of the somites,
absent proximal rib,
absent vertebral pedicles,
caudal body truncation,
decreased body length,
failure of somite differentiation,
incomplete somite formation,
neonatal lethality, complete penetrance,
short tail,
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.