fbxl5 Phenotypes

Phenotypes

XB-GENEPAGE-968564

Gene Symbol: fbxl5 Gene Name: F-box and leucine-rich repeat protein 5

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (27 sources): abnormal blood coagulation, abnormal ectoplacental cone morphology, abnormal embryo development, abnormal extraembryonic tissue physiology, abnormal hepatocyte morphology, abnormal iron level, abnormal mitochondrial physiology, decreased circulating unsaturated transferrin level, decreased liver iron level, embryonic growth retardation, embryonic lethality between somite formation and embryo turning, complete penetrance, embryonic lethality, complete penetrance, embryonic lethality during organogenesis, complete penetrance, increased circulating alanine transaminase level, increased circulating aspartate transaminase level, increased circulating iron level, increased circulating lactate dehydrogenase level, increased embryonic tissue cell apoptosis, increased intestinal iron level, increased partial thromboplastin time, increased sensitivity to induced morbidity/mortality, increased spleen iron level, liver hemorrhage, open neural tube, oxidative stress, pale liver, pericardial edema [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (27 sources): abnormal blood coagulation, abnormal ectoplacental cone morphology, abnormal embryo development, abnormal extraembryonic tissue physiology, abnormal hepatocyte morphology, abnormal iron level, abnormal mitochondrial physiology, decreased circulating unsaturated transferrin level, decreased liver iron level, embryonic growth retardation, [+]