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Summary Expression Phenotypes Gene Literature (32) GO Terms (8) Nucleotides (383) Proteins (59) Interactants (301) Wiki
XB-GENEPAGE-970177

top2a     DNA topoisomerase II alpha

Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (7 sources): abnormal circulating alkaline phosphatase level, abnormal embryo size, abnormal hematocrit, embryonic lethality prior to organogenesis, increased circulating alkaline phosphatase level, prenatal lethality prior to heart atrial septation, preweaning lethality, complete penetrance