cit Phenotypes

Phenotypes

XB-GENEPAGE-981096

Gene Symbol: cit Gene Name: citron rho-interacting serine/threonine kinase

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (31 sources): Abnormal cortical bone morphology, Agenesis of corpus callosum, Bulbous nose, Cerebellar hypoplasia, Failure to thrive, Global developmental delay, Gray matter heterotopia, Growth delay, Hyperreflexia, Hypertelorism, Hypoplasia of the brainstem, Hypoplasia of the frontal lobes, Intellectual disability, Intellectual disability, severe, Macrotia, Microcephaly, Microlissencephaly, Pachygyria, Reduced left ventricular ejection fraction, Renal agenesis, Seizure, Short stature, Simplified gyral pattern, Sloping forehead, Spasticity, Thick vermilion border, Thin upper lip vermilion, Unilateral renal agenesis, Upslanted palpebral fissure, Ventriculomegaly, Vesicoureteral reflux [+]
Mouse (17 sources): abnormal cerebellar Purkinje cell layer, abnormal cerebellum lobule morphology, abnormal cerebral hemisphere morphology, abnormal dentate gyrus morphology, abnormal diencephalon morphology, abnormal male germ cell apoptosis, abnormal spermatogonia proliferation, decreased brain weight, decreased male germ cell number, decreased midbrain size, increased neuron apoptosis, increased susceptibility to pharmacologically induced seizures, postnatal lethality, complete penetrance, reproductive system phenotype, small cerebellum, small olfactory bulb, thin cerebellar granule layer [+]
View all ortholog results at Monarch