ank3 Phenotypes

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Phenotypes

Gene Literature (3)

Nucleotides (366)

Interactants (125)

XB-GENEPAGE-989432

Gene Symbol: ank3 Gene Name: ankyrin 3, node of Ranvier (ankyrin G)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: ank3 assayed (4 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (17 sources): Aggressive behavior, Atypical behavior, Autistic behavior, Bruxism, Cleft palate, Delayed speech and language development, Generalized hypotonia, Hyperactivity, Hypotonia, Intellectual disability, Intellectual disability, mild, Intellectual disability, moderate, Large for gestational age, Macrocephaly, Seizure, Sleep abnormality, Spasticity [+]
Mouse (21 sources): abnormal action potential, abnormal axon initial segment morphology, abnormal axon morphology, abnormal brain wave pattern, abnormal bronchus epithelium morphology, abnormal hippocampus neuron morphology, abnormal kidney collecting duct epithelium morphology, abnormal node of Ranvier morphology, abnormal paranodal axoglial junction morphology, abnormal Purkinje cell morphology, convulsive seizures, decreased locomotor activity, decreased Purkinje cell number, impaired ability to fire action potentials, postnatal lethality, postnatal lethality, complete penetrance, premature death, prenatal lethality, incomplete penetrance, Purkinje cell degeneration, small cerebellum, thin cerebellar molecular layer [+]
View all ortholog results at Monarch