bcl2l11 Phenotypes

Summary

Expression

Phenotypes

Gene Literature (33)

XB-GENEPAGE-990116

Gene Symbol: bcl2l11 Gene Name: BCL2 like 11

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: bcl2l11 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (56 sources): abnormal B cell proliferation, abnormal CD4-positive, alpha beta T cell number, abnormal CD8-positive, alpha-beta T cell physiology, abnormal involution of the mammary gland, abnormal kidney morphology, abnormal leukopoiesis, abnormal lymphocyte physiology, abnormal mammary gland development, abnormal mammary gland duct morphology, abnormal plasma cell morphology, abnormal renal glomerulus basement membrane morphology, abnormal renal glomerulus morphology, abnormal response to infection, abnormal spleen marginal zone morphology, abnormal splenic cell ratio, abnormal sympathetic neuron morphology, decreased apoptosis, decreased B cell apoptosis, decreased double-positive T cell number, decreased physiological sensitivity to xenobiotic, decreased splenocyte apoptosis, decreased T cell apoptosis, decreased thymocyte apoptosis, dilated renal tubules, embryonic lethality during organogenesis, incomplete penetrance, glomerular crescent, hematopoietic system phenotype, immune system phenotype, increased anti-double stranded DNA antibody level, increased anti-histone antibody level, increased anti-nuclear antigen antibody level, increased anti-single stranded DNA antibody level, increased autoantibody level, increased B-2 B cell number, increased CD4-positive, alpha beta T cell number, increased CD8-positive, alpha-beta T cell number, increased double-negative T cell number, increased fibroblast apoptosis, increased follicular B cell number, increased granulocyte number, increased immature B cell number, increased marginal zone B cell number, increased mature B cell number, increased NK cell number, increased regulatory T cell number, increased renal glomerulus apoptosis, increased spleen weight, increased splenocyte number, increased susceptibility to autoimmune disorder, increased transitional stage B cell number, nervous system phenotype, no abnormal phenotype detected, premature death, renal cast, renal glomerular immunoglobulin deposits, spleen hyperplasia [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (56 sources): abnormal B cell proliferation, abnormal CD4-positive, alpha beta T cell number, abnormal CD8-positive, alpha-beta T cell physiology, abnormal involution of the mammary gland, abnormal kidney morphology, abnormal leukopoiesis, abnormal lymphocyte physiology, abnormal mammary gland development, abnormal mammary gland duct morphology, abnormal plasma cell morphology, [+]