nek8 Phenotypes

Phenotypes

XB-GENEPAGE-990377

Gene Symbol: nek8 Gene Name: NIMA-related kinase 8

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (19 sources): Aortic valve stenosis, Asplenia, Cholestasis, Cystic renal dysplasia, Enlarged kidney, Femoral bowing, Hepatic fibrosis, Hepatomegaly, Hypertrophic cardiomyopathy, Nephronophthisis, Oligohydramnios, Patent ductus arteriosus, Polycystic kidney dysplasia, Pulmonary hypoplasia, Pulmonic stenosis, Renal insufficiency, Situs inversus totalis, Talipes equinovarus, Truncus arteriosus [+]
Mouse (18 sources): abnormal maternal nurturing, atrioventricular septal defect, decreased effector memory CD4-positive, alpha-beta T cell number, decreased effector memory CD8-positive, alpha-beta T cell number, dilated kidney collecting duct, dilated proximal convoluted tubule, increased CD4-positive, alpha beta T cell number, increased circulating creatinine level, increased kidney weight, increased mean systemic arterial blood pressure, increased susceptibility to induced colitis, increased systemic arterial diastolic blood pressure, increased systemic arterial systolic blood pressure, kidney medulla cyst, premature death, renal glomerulus cyst, respiratory system phenotype, right pulmonary isomerism [+]
View all ortholog results at Monarch