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Summary Expression Phenotypes Gene Literature (0) GO Terms (10) Nucleotides (41) Proteins (29) Interactants (0) Wiki
XB-GENEPAGE-489736
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 cd40lg

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CD40 ligand (TNF superfamily, member 5, hyper-IgM syndrome)

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( Nomenclature history )

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tumor necrosis factor (ligand)

Protein Function :
Acts as a ligand for integrins, specifically ITGA5:ITGB1 and ITGAV:ITGB3; both integrins and the CD40 receptor are required for activation of CD40-CD40LG signaling, which have cell-type dependent effec...[+]


InterPro :
CD40L, TNF CS, TNF dom, Tumour necrosis fac-like dom

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Diseases: 


Disease Ontology:
CD40 ligand deficiency

External Links:
 
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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