The chrnb3 protein functions as a neuronal nicotinic acetylcholine receptor subunit, forming ligand-gated ion channels permeable to cations upon acetylcholine binding. It is a membrane-bound receptor l...[+]

The chrnb3 protein functions as a neuronal nicotinic acetylcholine receptor subunit, forming ligand-gated ion channels permeable to cations upon acetylcholine binding. It is a membrane-bound receptor localized to the cell membrane. Expression is documented in the brain, including the telencephalon, diencephalon, mesencephalon, and retina, with additional expression found in cranial ganglia and the spinal cord. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD