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Summary Expression Phenotypes Gene Literature (0) GO Terms (24) Nucleotides (141) Proteins (74) Interactants (212) Wiki
XB-GENEPAGE-6067220
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 pik3r1

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phosphoinositide-3-kinase regulatory subunit 1

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grb1 , p85-alpha , pik3r1-a , pik3r1-b ( Nomenclature history )

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Protein Function :
Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane.


InterPro :
PI3kinase P85 nSH2, PI3K P85 iSH2, Rho GTPase activation prot, SH3 domain, [+]

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Diseases: 


Disease Ontology:
agammaglobulinemia [+]

External Links:
 
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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