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Summary Expression Phenotypes Gene Literature (15) GO Terms (18) Nucleotides (122) Proteins (59) Interactants (105) Wiki
XB-GENEPAGE-962371
???displayGene.symbol???:
 ldlr

???displayGene.name???: 
low density lipoprotein receptor

???displayGene.synonyms???
fhc , ldlcq2 , ldlr-a , ldlr-b ( Nomenclature history )

???displayGene.geneFunction???
EGF-like calcium ion binding

Protein Function :
Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin...[+]


InterPro :
JHD, Znf RING/FYVE/PHD, JmjC dom, GPCR 2 extracellular dom, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
familial hypercholesterolemia

External Links:
 
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info