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Summary Expression Phenotypes Gene Literature (2) GO Terms (8) Nucleotides (211) Proteins (57) Interactants (73) Wiki
XB-GENEPAGE-950143
???displayGene.symbol???:
 erlin2

???displayGene.name???: 
ER lipid raft associated 2

???displayGene.synonyms???
erlin2-a , erlin2-b , spfh2 ( Nomenclature history )

???displayGene.geneFunction???
Prohibitin-related membrane protease subunits

Protein Function :
Mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Promotes sterol-accelerated ERAD of HMGCR. Involved in regulation of cellular cholest...[+]


InterPro :
Band 7, Erlin1/2, DPH6/MJ0570, Diphthami syn dom, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
hereditary spastic paraplegia 18

External Links:
 
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info