The nfkb2 protein is a transcription factor of the rel homology domain family, forming homodimers or heterodimers with other rel proteins to bind dna at kappa-b sites. It is involved in immune system r...[+]

The nfkb2 protein is a transcription factor of the rel homology domain family, forming homodimers or heterodimers with other rel proteins to bind dna at kappa-b sites. It is involved in immune system regulation and development, with its processed p52 subunit translocating from the cytoplasm to the nucleus. Expression is detected in the oocyte, early embryo, brain, eye, and pronephros. [-]

             common variable immunodeficiency 10

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD