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Summary Expression Phenotypes Gene Literature (11) GO Terms (49) Nucleotides (185) Proteins (54) Interactants (291) Wiki
XB-GENEPAGE-1008433
???displayGene.symbol???:
 map3k1

???displayGene.name???: 
mitogen-activated protein kinase kinase kinase 1

???displayGene.synonyms???
mapkkk1 , mekk , mekk1 ( Nomenclature history )

???displayGene.geneFunction???
MEKK and related serine/threonine protein kinases

Protein Function :
Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. May phosphorylate the MAPK8/JNK1 kinase. Activates CHUK and...[+]


InterPro :
ARM-like, Kinase-like dom sf, MAP kinase kinase kinase, Prot kinase dom, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
46,XY complete gonadal dysgenesis [+]

MIM:
46,XY SEX REVERSAL 6; SRXY6

External Links:
 
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info