Return to search results Title: In vivo T-box Transcription Factor Profiling Reveals Joint Regulation of Embryonic Neuro-mesodermal Bipotency

Summary

Brachyury (Xbra/Xbra3) knock-down embryos of the frog Xenopus tropicalis were profiled to quantify neuro-mesodermal cell fate switches at a transcriptional level.

Contributors: George Gentsch, George Gentsch, James Smith

Experiment Type: Transcriptional profiling of Xbra/Xbra3 double morphants at early tadpole stage (RNA-Seq) in biological triplicates.

Experiment Reagents: hbg1 cMO1, tbxt.2 MO3, tbxt.2 MO4, [-][+]


Article: XB-ART-47416, PubMed

Source: NCBI GEO, Xenbase Download

Sample	View		GSMs	Assay Type
WE + hbg1 MO - NF32 GSM1183059  GSM1183060  GSM1183061  RNA-Seq Xtr   [-] [+] Background: Xtr.Outbred Manipulations: Manipulation Type Reagent Target Gene Stage Treatment Area morpholino injection hbg1 cMO1 hbg1 NF stage 1 zygote Conditions: Tissue Assay Stages ChIP Antibody embryo NF stage 32      WE + tbxt.2 MO + tbxt MO - NF32 DEG GSM1183056  GSM1183057  GSM1183058  RNA-Seq Xtr   [-] [+] Background: Xtr.Outbred Manipulations: Manipulation Type Reagent Target Gene Stage Treatment Area morpholino injection tbxt.2 MO3 tbxt.2 NF stage 1 zygote morpholino injection tbxt MO2 tbxt NF stage 1 zygote morpholino injection tbxt MO3 tbxt NF stage 1 zygote morpholino injection tbxt.2 MO4 tbxt.2 NF stage 1 zygote Conditions: Tissue Assay Stages ChIP Antibody embryo NF stage 32   WE - NF20 GSM1183062  RNA-Seq Xtr   [-] [+] Background: Xtr.Outbred Conditions: Tissue Assay Stages ChIP Antibody embryo NF stage 20

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