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Activity-independent and activity-dependent mechanisms work in concert to regulate neuronal growth, ensuring the formation of accurate synaptic connections. CPG15, a protein regulated by synaptic activity, functions as a cell-surface growth-promoting molecule in vivo. In Xenopus laevis, CPG15 enhanced dendritic arbor growth in projection neurons, with no effect on interneurons. CPG15 controlled growth of neighboring neurons through an intercellular signaling mechanism that requires its glycosylphosphatidylinositol link. CPG15 may represent a new class of activity-regulated, membrane-bound, growth-promoting proteins that permit exquisite spatial and temporal control of neuronal structure.
Antal,
Tectal neurons of the frog: intracellular recording and labeling with cobalt electrodes.
1986, Pubmed
Antal,
Tectal neurons of the frog: intracellular recording and labeling with cobalt electrodes.
1986,
Pubmed
Bodnarenko,
Stratification of ON and OFF ganglion cell dendrites depends on glutamate-mediated afferent activity in the developing retina.
1993,
Pubmed
Brümmendorf,
Structure/function relationships of axon-associated adhesion receptors of the immunoglobulin superfamily.
1996,
Pubmed
Cheng,
Identification and cloning of ELF-1, a developmentally expressed ligand for the Mek4 and Sek receptor tyrosine kinases.
1994,
Pubmed
Constantine-Paton,
Patterned activity, synaptic convergence, and the NMDA receptor in developing visual pathways.
1990,
Pubmed
Davis,
Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity.
1994,
Pubmed
Drescher,
In vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases.
1995,
Pubmed
Friedman,
Eph receptor tyrosine kinases and their ligands in neural development.
1996,
Pubmed
Goodman,
Developmental mechanisms that generate precise patterns of neuronal connectivity.
1993,
Pubmed
Katz,
Relationships between segregated afferents and postsynaptic neurones in the optic tectum of three-eyed frogs.
1988,
Pubmed
Kossel,
Relationships between dendritic fields and functional architecture in striate cortex of normal and visually deprived cats.
1995,
Pubmed
Lund,
Postnatal development of thalamic recipient neurons in the monkey striate cortex: II. Influence of afferent driving on spine acquisition and dendritic growth of layer 4C spiny stellate neurons.
1991,
Pubmed
Naeve,
Neuritin: a gene induced by neural activity and neurotrophins that promotes neuritogenesis.
1997,
Pubmed
Nakamoto,
Topographically specific effects of ELF-1 on retinal axon guidance in vitro and retinal axon mapping in vivo.
1996,
Pubmed
Nedivi,
A set of genes expressed in response to light in the adult cerebral cortex and regulated during development.
1996,
Pubmed
Nedivi,
Numerous candidate plasticity-related genes revealed by differential cDNA cloning.
1993,
Pubmed
Pandey,
Cell signalling. Receptor orphans find a family.
1995,
Pubmed
Pettit,
Potentiated transmission and prevention of further LTP by increased CaMKII activity in postsynaptic hippocampal slice neurons.
1995,
Pubmed
Shatz,
Impulse activity and the patterning of connections during CNS development.
1991,
Pubmed
SHOLL,
Dendritic organization in the neurons of the visual and motor cortices of the cat.
1953,
Pubmed
Tieman,
Exposure to lines of only one orientation modifies dendritic morphology of cells in the visual cortex of the cat.
1983,
Pubmed
Wong,
Remodeling of retinal ganglion cell dendrites in the absence of action potential activity.
1992,
Pubmed
Wu,
Stabilization of dendritic arbor structure in vivo by CaMKII.
1998,
Pubmed
,
Xenbase
Wu,
Infection of frog neurons with vaccinia virus permits in vivo expression of foreign proteins.
1995,
Pubmed
,
Xenbase
Zou,
Expression of constitutively active CaMKII in target tissue modifies presynaptic axon arbor growth.
1996,
Pubmed
,
Xenbase
