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Are stretch-sensitive channels in molluscan cells and elsewhere physiological mechanotransducers?
Morris CE
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Single-channel recordings of dozens of cell types, including invertebrate (molluscan) and vertebrate heart cells, reveal stretch-sensitive ion channels. The physiological roles of these channels are undoubtedly diverse but it is usually assumed that the roles they play are related to the channels' mechanosensitive gating. Whether this assumption is valid remains to be seen. Attempts to connect the single-channel observations with the mechanical aspects of physiological or developmental processes are discussed. In the case of molluscan cells, recent work suggests that their stretch channels have physiological functions unrelated to mechanosensitive gating.
Bear,
Calcium-permeable channels in rat hepatoma cells are activated by extracellular nucleotides.
1991, Pubmed
Bear,
Calcium-permeable channels in rat hepatoma cells are activated by extracellular nucleotides.
1991,
Pubmed
Bear,
A nonselective cation channel in rat liver cells is activated by membrane stretch.
1990,
Pubmed
Bédard,
Channels activated by stretch in neurons of a helix snail.
1992,
Pubmed
Belardetti,
Neuronal inhibition by the peptide FMRFamide involves opening of S K+ channels.
,
Pubmed
Belardetti,
The growth cones of Aplysia sensory neurons: Modulation by serotonin of action potential duration and single potassium channel currents.
1986,
Pubmed
Bevan,
Pressure and flow-dependent vascular tone.
1991,
Pubmed
Brezden,
The peptide FMRFamide activates a divalent cation-conducting channel in heart muscle cells of the snail Lymnaea stagnalis.
1991,
Pubmed
Chamberlin,
Anisosmotic cell volume regulation: a comparative view.
1989,
Pubmed
Erxleben,
Stretch-activated current through single ion channels in the abdominal stretch receptor organ of the crayfish.
1989,
Pubmed
Falke,
Activity of ion channels during volume regulation by clonal N1E115 neuroblastoma cells.
1989,
Pubmed
Filipovic,
A calcium-permeable stretch-activated cation channel in renal proximal tubule.
1991,
Pubmed
,
Xenbase
Franco,
Calcium entry through stretch-inactivated ion channels in mdx myotubes.
1990,
Pubmed
Gorczyca,
Single-channel K+ currents in Drosophila muscle and their pharmacological block.
1991,
Pubmed
Guharay,
Stretch-activated single ion channel currents in tissue-cultured embryonic chick skeletal muscle.
1984,
Pubmed
Gustin,
A mechanosensitive ion channel in the yeast plasma membrane.
1988,
Pubmed
Hisada,
Hyperpolarization-activated cationic channels in smooth muscle cells are stretch sensitive.
1991,
Pubmed
Hudspeth,
How the ear's works work.
1989,
Pubmed
Iwasa,
Stretch sensitivity of the lateral wall of the auditory outer hair cell from the guinea pig.
1991,
Pubmed
Kater,
Regulation of growth cone behavior by calcium.
1991,
Pubmed
Kimelberg,
Swelling-induced changes in electrophysiological properties of cultured astrocytes and oligodendrocytes. II. Whole-cell currents.
1990,
Pubmed
Kirber,
Stretch-activated ion channels in smooth muscle: a mechanism for the initiation of stretch-induced contraction.
1988,
Pubmed
Lansman,
Single stretch-activated ion channels in vascular endothelial cells as mechanotransducers?
,
Pubmed
Martinac,
Pressure-sensitive ion channel in Escherichia coli.
1987,
Pubmed
Martinac,
Mechanosensitive ion channels of E. coli activated by amphipaths.
1990,
Pubmed
Medina,
Stretch-activated ion channels modulate the resting membrane potential during early embryogenesis.
1988,
Pubmed
Medina,
Sensitivity of stretch-activated K+ channels changes during cell-cleavage cycle and may be regulated by cAMP-dependent protein kinase.
1991,
Pubmed
Moody,
A nonselective cation channel activated by membrane deformation in oocytes of the ascidian Boltenia villosa.
1989,
Pubmed
Morris,
Stretch-inactivated ion channels coexist with stretch-activated ion channels.
1989,
Pubmed
Morris,
Failure to elicit neuronal macroscopic mechanosensitive currents anticipated by single-channel studies.
1991,
Pubmed
Morris,
Mechanosensitive ion channels.
1990,
Pubmed
Pellegrino,
Stretch-activated cation channels with large unitary conductance in leech central neurons.
1990,
Pubmed
Piomelli,
Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells.
,
Pubmed
Sachs,
Mechanical transduction in biological systems.
1988,
Pubmed
Sigurdson,
Stretch-activated ion channels in growth cones of snail neurons.
1989,
Pubmed
Sokabe,
Quantitative video microscopy of patch clamped membranes stress, strain, capacitance, and stretch channel activation.
1991,
Pubmed
Sokabe,
The structure and dynamics of patch-clamped membranes: a study using differential interference contrast light microscopy.
1990,
Pubmed
Zagotta,
Single-channel analysis of four distinct classes of potassium channels in Drosophila muscle.
1988,
Pubmed
Zhou,
A mechanosensitive channel in whole cells and in membrane patches of the fungus Uromyces.
1991,
Pubmed
